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[QUOTE=Guest-IJT;108514][b]Name [/b]: Ajay Abhyankar [b]Email [/b]: abhyankarajay AT rediffmail.com [b]Designation / Skillset[/b] : Manager R&D I had more than eight years of research experience including academic and as a scientific professional. In my current employment I am responsible for coordinating the research activities of R&D related to rapid test development and production of monoclonal antibodies (In-Vivo & In-Vitro) for the organization. In my past employment I was engaged in production (In-Vivo & In-Vitro)and new developments of monoclonal antibodies for suitable applications. I had worked in Vaccine development dept. in Nicholas Piramal research center for the development of promising HSV vaccine. I had developed monoclonal antibodies against dengue recombinant protein and native JE protein during my PhD tenure. A manuscript was submitted for preparing Anti-B blood grouping antibody in national journal. I have more than five years of research experience, in Hybridoma technology, Antibody Purification techniques, Rapid test development and all immunological assays requires for diagnostics group. [u][b]Resume[/b][/u] : Executive summary Eight years of research experience including corporate and academic research. Development of group and type specific monoclonal antibodies against dengue recombinant protein as a part of PhD thesis. Developed diagnostics methods for the dengue and Japanese encephalitis viruses, in addition to dengue virus antibody detection kit DENSTICK are the major achievement. In Vivo & In vitro propagation of viruses and isolation of viruses, Handled various cell lines e.g. C6/36, LLC MK2, BHK-21, Vero, HeLa, HL-60, J774 & THP-1. Serological tests like ELISA, ICT for identification of viruses in clinical samples were attempted. In-Vivo & In-Vitro production (Hollow fiber based bioreactor) of monoclonal antibodies for blood grouping reagents, cancer markers and immuno-histology related antibodies. Development of new clones against salmonella & HBSAg and other recombinant proteins. Successfully developed Anti-B clone as a blood grouping reagent. Six research papers are published in international journals of repute, One under peer review. Professional Experience ADVY Chemical Pvt Ltd., Thane, Maharashtra, March’ 11 - Present Manager R&D Development of rapid tests for diseases like Malaria, Dengue, Syphlis, Troponin-I. In-Vivo & In-Vitro production (bioreactor) of monoclonal antibodies for in-house manufacturing. SPAN DIAGNOSTICS LTD, Sachin, Surat, India June 07- Feb 2011. Asst Manager R&D (Hybridoma) In-Vivo & In-Vitro production (Hollow fiber based bioreactor) of monoclonal antibodies for blood grouping reagents, cancer markers and immuno-histology related antibodies. Nicholas Piramal Research Center, Goregaon, Mumbai, India June 06- May 07 Junior Research Scientist (Pharmacology, Vaccine Development) [b]Achievements [/b]: Design and establish new methods for antioxidant molecule screening. Defence Research & Development Establishment, Gwalior, India Jan 03 – May 06; Research Fellow/PhD Scholar (Virology division) [b]Achievements [/b]: Process development for field based dengue, JE diagnostic kits. Development of monoclonal antibodies against Dengue viral recombinant protein for dengue diagnosis. Development of monoclonal antibodies against JE viral protein for diagnosis.. Cadbury India Limited, Malanpur, Bhind, India Sep 99- March 02 Trainee Asst quality officer (Quality Department) [b]Achievements [/b]: Process develops for microbiological testing of Raw/finished materials. Process develops for quality testing and hygiene. Academics PhD in Microbiology Jiwaji University, Gwalior, India Defence Research & Development Establishment, Gwalior, India (One of the top Govt. Defence research lab) Jan 2003 – Nov. 2008 (Division of virology; Mentor Dr A. M. Jana) [b]Achievements [/b]: - Development of monoclonal antibodies against dengue recombinant protein antigen. - During thesis work got some group specific and type specific clones against novel recombinant protein which have been explored in details and pipeline in publication. - Publish six research papers in international journals. Master of Science in Applied Microbiology Jiwaji University, Gwalior, India July 97- June 99 Cancer Hospital & Research Institute, Gwalior,. India Bachelor of Science in Botany, Zoology and Chemistry Jiwaji University, Gwalior, India July 94- June 97 Govt Autonomous Science College, Gwalior, India Advance Diploma in Bioinformatics Computer Education Bioinformatics Research & Training Center, Gwalior, India. Sep.’ 03-Aug’ 04 Diploma in Computer Application July 98- June 99 Makhanlal Chaturvadei Rashtriya Pratrakarita Vishwavidylaya, Bhopal, India Conference/Seminar/ Symposia attended Recent Advances in diagnostics virology “DRDE CEP course, July 2005, DRDE, Gwalior. Evaluation of a dengue dipstick ELISA with commercial immunodiagnostics kits. 32nd Annual conference of Indian Immunological Society, Poster presented on during 24-27 November, 2005, PIGMER, Chandigarh. [b]Serotype Shift [/b]: Implications for increased incidences of Dengue in Madhya Pradesh, 21st Young scientist congress sponsored by M.P. council of science and technology, Bhopal, 28th Feb 01st March 2006, Awadesh Pratap Singh University, Rewa, M.P. Training on for bulk production of monoclonal antibody based on Hollow fiber bioreactors in SAPN-Sarl, Compiegne, France from 21st July 07 to 20th August 07. Publications [b]Abhyankar AV, Bhargava R, Jana AM, Sahni AK and Rao PVL. Production and characterization of monoclonal antibody specific to recombinant dengue multi-epitope protein. Jun 2008,Hybridoma, 27(3) [/b]:191-8. Abhyankar AV, Dash PK, Saxena P, Bhargava R, Parida MM, Jana AM, Sahni AK and Rao PVL. Comparative Evaluation of a Dipstick ELISA with Commercial assays for Dengue IgM antibodies. Viral Immunology, 19#4 Dec 2006. [b]Dash PK, Saxena P, Abhyankar A, Bhargava R & Jana AM., March 2005. “Serological and Molecular diagnosis of dengue outbreak in Northern India” South East Asian J. Trop. Med. & Pub. Hlth. 36 (1) [/b]: 3383. Priyabrata Pattnaik, Ambuj, Ajay Abhyankar, Paban Kumar Dash, Man Mohan Parida and P V L Rao. Fusogenic peptide as diagnostic marker for detection of Flavivirus. J. Postgrad. Med., 52(3). [b]P. K. Dash, M. M. Parida, P. Saxena, A. Abhyankar, C. P. Singh, K. N. Tewari, A. M. Jana, K. Sekhar, P. V. L. Rao. Reemergence of Dengue Virus Type-3 (Subtype-III) in India [/b]: Implications for Increased Incidences of DHF & DSS. In Virology J. M. M. Parida, P. K. Dash, N. K. Tripathi, Ambuj, S. R. Santhosh, P. Saxena, S. Agarwal, A. K. Sahani, S. P. Singh, A. K. Rathi, R. Bhargava, A. Abhyankar, S. K. Verma, P. V. L. Rao, K. Sekhar. Japanese encephalitis outbreak investigation, Gorakhpur, India, 2005. In Emerging Infectious Diseases. GenBank Submission Nine dengue virus type 3 C-prM gene junction sequences published in NCBI Gen bank. The Gen bank Accession Nos. AY770511-3 & DQ323037-42. Book Chapter [b]P. K. Dash, P. Saxena, A. Abhyankar, R. Bhargava, P. Pattnaik, A. M. Jana (2005). Molecular characterization of NS1 gene of an Indian isolate of Dengue virus type-2. In [/b]: Garg, D and Singh, A. (Eds); Bioinformatics Computing; Allied Publishers Pvt. Ltd., New Delhi (ISBN 81-7764-631-1), p16-22. Papers Presented/ Abstracted in Symposia/Conferences [b]1. P. K. Dash, M. M. Parida, P. Saxena, A. Abhyankar, A. M. Jana, P. V. L. Rao, C. P. Singh, K. N. Tewari, K. Sekhar. Reemergence of Dengue virus type-3 (Genotype III) [/b]: Implications for increased incidence of DHF & DSS. In International Symposium on arthropod borne viruses during 7-10 February 2006 at ICRISAT, Hyderabad. 2. P. K. Dash, M. M. Parida, P. Saxena, P. Pattnaik, A. Abhyankar, R. Bhargava, A. M. Jana. Molecular characterization of recently circulating Indian dengue virus type-2’. In Second Regional Dengue Research Network meeting during 28-30 September 2005 at Singapore. 3. P. K. Dash, P. Saxena, A. Abhyankar, R. Bhargava, P. Pattnaik and A. M. Jana. Molecular characterization of NS1 gene of an Indian isolate of Dengue virus type-2. In National Conference on Bioinformatics Computing during 18-19 March, 2005 at TIET, Patiala. 4. P. Pattnaik, P. K. Dash, Ambuj, P. Saxena, A. Abhyankar, A. R. Rao, N. Khanna and A. M. Jana. Expression, purification and functional evaluation of recombinant dengue multi epitope protein (r-DMEP). In International Symposium on Emerging Viral Infections- New Frontiers & Challenges during 11-13 October, 2004 at NIV, Pune. 5. P. K. Dash, P. Saxena, A. Abhyankar, R. Bhargava, P. Pattnaik and A. M. Jana. Emergence of dengue virus type-3 in a dominant form in India. In International Symposium on Emerging Viral Infections- New Frontiers & Challenges during 11-13 October, 2004 at NIV, Pune. [b]Dissertation [/b]: 4 students have been undergone 6 months training under my supervision. [b]References [/b]: [b]1. Name [/b]: Dr A.M. Jana Vice-Principal, Professor & Head [b]Department of Biotechnology, College of Life Sciences, Cancer Hospital & Research Institute, Gwalior-474009, Madhya Pradesh (M.P.) India Ph [/b]: +91-0751-2336502, Mobile: 098262 40712 amjana AT rediffmail.com [b]2. Name [/b]: Dr P. Pattnaik [b]Occupation or Position [/b]: Group Leader, Bioprocess Division [b]Address [/b]: Millipore India Pvt Ltd. Bangalore, pattnaik AT eudoramail.com [b]3. Name [/b]: Dr PVL Rao, [b]Position [/b]: Head, Division of Virology [b]Address [/b]: Defence Research & Development Establishment, Gwalior. pvlrao AT rediffmail.com Signature of Candidate [b]Place [/b]: Thane Date: ------------------------------------------------------- More Information about this submission and submitter:- ___________________________________________________ Submission ID : 4207219 Date & Time : 3rd Jun 2011 12:28 PM (UTC) IP Address : 59.181.102.103 Browser Info : Mozilla/4.0 (compatible; MSIE 7.0; Windows NT 5.1; InfoPath.2) Predicted Country : India[/QUOTE]
