Organisation : Pondicherry University
Announcement : Download Admit Card
Name of Exam : BINC 2017
Part-I Bioinformatics National Certification Examination

Download your admit card here : https://cdn.digialm.com/EForms/confi...257/login.html
Home Page : http://www.pondiuni.edu.in/exams/binc/index.php

Download Admit Card :
Availability of admit card for Paper-I on the website March 10, 2017
Examination dates Part I (Paper I) - March 23, 2017

Important points to note:
For Paper I there will be negative marking of 0.25 for every wrong answer.
The list of successful candidates in the Paper I will be announced on March 27, 2017 on the website.
Candidates securing 40% or above marks in Paper I ONLY will be eligible to appear for Paper II and III.
Candidates scoring a minimum of 40% or above in each papers(Paper I, Paper II & Paper III) will be certified.
Final list will be displayed at the BINC website.

BINC Biology Syllabus: Basic
Cell Biology and Genetics :
Basic aspects of Prokaryotic and eukaryotic cells (plant and animal cells); membranes and cellular compartments, cell organelles, structure and function, visualizing cells.
Cell motility and shape: cytoskeletal elements, cilia and flagella; motor proteins
Cell-cell interactions: Intercellular junctions
Cell cycle and its regulation, events during mitosis and meiosis, Programmed Cell Death.
Concepts of Bioenergetics, respiration, electron transport systems.
Concepts of gene: Allele, multiple alleles, pseudoallele, complementation tests.
Mendelian principles: Inheritance, sex linked inheritance, Dominance, segregation, independent assortment.
Mutations: Types, causes and detection, germline versus somatic mutations, Mutant types – lethal, conditional, biochemical, loss of function, gain of function, point/deletion/insertional mutations, DNA repair
Chromosomal Variations: Structural and numerical abnormalities: Aneuploidy, Euploidy, Polypoidy, Trisomy, monosomy, nullisomy.
Basic concepts in immunology, Innate and adaptive, humoral and cell mediated immunity and antigen-antibody interaction
Concepts of development and pattern formation. – C. elegans, Drosophila, Frog embryo development and neural development.

Molecular Biology :
DNA and RNA: Structure, physical and chemical properties, Types of DNA and RNA. DNA as a genetic material.
Prokaryotic and eukaryotic genome organization and structure
Basic concepts of replication – Experiments to prove Semi conservative replication, Prokaryotic – rolling circle replication and Eukaryotic replications, Prokaryotic gene expression – Lac operon, trp operan, factors involved in gene regulations, mechanisms of gene expression in Eukaryotes, basic mechanisms of transcription and translation
Mechanisms of genome alterations: Recombination, mutation, inversion, duplication, transposition.

Biochemistry :
Carbohydrates and lipids, their importance in cells
Proteins: Amino acids and their physico-chemical properties, peptide bond and peptides
Nucleic acids: Nucleosides, nucleotides, RNA and DNA. Denaturation and renaturation of DNA
Enzymes: Units of activity, coenzymes and metal cofactors, temperature and pH effects, MichaelisMenten kinetics, inhibitors and activators, active site
Carbohydrate metabolism: Glycolysis, gluconeogenesis, glycogenolysis, glycogenesis, TCA cycle and oxidative phosphorylation
Pentose phosphate pathway; hormonal control, ß-oxidation and biosynthesis of fatty acids
Transamination and deamination of amino acids, ketogenic and glycogenic amino acids, urea cycle
Purine and pyrimidine biosynthesis

Suggested Books for Reading:
1. Life, the biology of science, 10th edition, David Sadava
2. Genetics: A conceptual approach, 5th Edition, Benjamin Pierce.
3. Principles of Biochemistry by Lehninger
4. The Molecular biology of the Cell, 5th Edition, Bruce Alberts
5. Genes X by B. Lewin
6. Essential Cell Biology 2nd Ed B.Alberts, D.Bray, K.Hopkin and A.Johnson
7. Biochemisty, 6th Edition Berg, Jermy M., Tymoczko, John L and Styer, Lubert
8. Biochemistry Vol 1: Biomolecules, mechanisms of enzyme action and metabolism Voet, D and Voet, J.
9. Molecular Biology of the Gene, Watson, JD., Hopkins, NH., Roberts, JW and Steitz, JA