Tuberculosis Research Centre Chennai Recruitment 2011 www.trc-chennai.org : Scientist

[muthukalee]

Name of the Organization : Tuberculosis Research Centre
Location : Chennai
Name of the Post : Scientist

TUBERCULOSIS RESEARCH CENTRE
EPIDEMIOLOGY UNIT
(INDIAN COUNCIL OF MEDICAL RESEARCH)
CHENNAI – 600 031

Applications are invited upto 7th September 2011 for the following posts of Scientist ‘B’ in the Pay Band PB-3 Rs.15600-39100 + Grade pay Rs.5400/- at the ICMR’s Tuberculosis Research Centre, Epidemiology Unit, Chennai:

Name of the post : Scientist ‘B’ (Medical)
Number of vacancies : One
Age as on 07. 09.11 : Not exceeding 35 years
Essential qualifications : MBBS degree recognized by MCI

Name of the post : Scientist ‘B’ (Statistics)
Number of vacancies : One
Age as on 07. 09.11 : Not exceeding 35 years
Essential qualifications : First class Master’s Degree in Statistics / Biostatics from a recognized University (OR) Second class M.Sc + Ph.D degree in Statistics / Biostatistics from a recognized university

• Application forms and other information can be obtained from the Office of the
Director –in-Charge,
Tuberculosis Research Centre,
Epidemiology Unit, Mayor VR Ramanathan Road,
Chetput, Chennai – 600 031

in person or downloaded from ICMR website www.icmr.nic.in, www.trc-chennai.org on or before the closing date. Application forms duly completed in all respects and signed by the applicant should be sent on the above mentioned address and should reach the Centre on or before the closing date along with the attested copies of the certificates in support of date of birth, educational qualification, experience etc and a crossed Indian Postal Order (IPO) for Rs.100/- (Rupees One Hundred only) payable to the Director, Tuberculosis Research Centre, Chennai. SC/ST and physically handicapped candidates (PH) are exempted from the application fee payable in form of IPO. IPOs are payable by all other candidates including ICMR employees. Incomplete / late applications or without postal orders will not be entertained. Application received after the closing date for whatever reason is liable to be rejected. Application with evidence for proof of age (HSC certificate, educational qualifications and supporting documents for proof of age (HSC certificate), educational qualifications and supporting documents of experiences to be furnished for consideration. Unsigned/ Incomplete application or application without supportive evidence asked for/ without postal order application received late shall be summarily rejected.

General Instructions :
1) This is a job / career / vacancy / recruitment posting from on : Tuberculosis Research Centre at the Post Scientist for post of Scientist.
2) For more details refer company website of Tuberculosis Research Centre.
3) You can send your resume / CV to the careers e-mail id of the company (Tuberculosis Research Centre).
4) Source of this info is the company website / internet on the date of publishing.

[Guest-IJT]

Name : Dr. Surajit Pathak
Email : surajit.pathak AT gmail.com
Designation / Skillset : Research Scientist
Dear Sir/Madam,
HR Manager
I would like to introduce myself as Surajit Pathak, M.Sc. Ph.D. working as a post doctoral fellow from 2009 March - till date in the Department of Surgical and Gastroenterological Sciences, University of Padova, Italy.
I am greatly interested in the research works undergoing in your company. I’ve opted to explore the possibility of working in your group as a scientist, if permissible.
During my term of doctoral and post doctoral training I have gathered expertise in the field of Stem cell biology, Molecular and Cell Biology, Toxicology, Immunology and Cancer Genetics. My present work involves firstly, the influence of conditioned medium of intestinal sub-epithelial myofibroblasts on hematopoeitic stem cell differentiation; and secondly possible role of microRNAs in inflammatory bowel disease patients.
My doctoral works dealt with induced hepatocarcinoma in mice and rats and arsenic toxicity in humans.
I am attaching my detailed CV for your kind perusal and shall be pleased to provide you with any further information, if you so desire. I feel my knowledge, skills, and abilities will offer a well-rounded approach to your research group, if I get a chance to work in your company.
Thank you for taking time to view my research experience. I hope that you will be kind enough to consider my application favorably.
Thanking you in anticipation.
With very best regards,
Sincerely Yours,
Dr. Surajit Pathak

Resume :
SURAJIT PATHAK, M.Sc, Ph.D.
BRIEF OVERVIEW
- Post-Doctoral Researcher from March 2009 in Department of Surgery and Gastroenterology, University of Padova, Padova, Italy.
- Ph.D. in Zoology from Department of Zoology, University of Kalyani.
- Acquired knowledge and understanding of topics like; Toxicology, Molecular Biology, Immunology, Stem Cell Research, Cancer Genetics.
- Abilities in handling multiple priorities, with a bias for action and a genuine interest in personal and professional development.
- Extremely motivated and career-oriented professional capable to work in a professional environment with a positive attitude.
ACADEMIA
- Ph.D. in Zoology from Department of Zoology, University of Kalyani in 2007.
- Qualified Graduate Aptitude Test in Engineering (GATE-2004) with 90 percentile.
- M.Sc. in Zoology (Endocrinology and Reproductive Physiology) from University of Kalyani, West Bengal in 2002.
- B.Sc. (Honours) in Zoology from University of Kalyani, West Bengal in 2000.
- 12th from West Bengal Council of Higher Secondary Education in 1996.
- 10th from West Bengal Board of Secondary Education in 1994.
TITLE OF M.Sc. DISSERTATION AND Ph.D. THESIS
M.Sc. Part-II
DISSERTATION Title : Role of Calcium Ion in Cell Signaling with Special Emphasis on Ovarian Regulation.
Ph.D.
Thesis Title : Assessment of Anti-Tumorigenic, Anti-Cytotoxic and Anti-Genotoxic Potentials of a Homeopathic Drug, Lycopodium Clavatum in Mice.
Supervisor Name : Professor Anisur Rahman Khuda-Bukhsh, Department of Zoology, University of Kalyani, Kalyani, West Bengal, India.
RESEARCH EXPERIENCE
- After submission of Ph.D. thesis in March 2007 joined as a PDF in Department of Zoology, University of Kalyani in the “Boiron”, Lyon, France sponsored International Collaborative Research Project
Title : A Comprehensive Study of Arsenic Toxicity in human living in arsenic contaminated zone in West Bengal, India.
- Then won the Scholarship for Students with LAUREA MAGISTRALE in Medicine and Surgery or Biological Sciences” in March 2009 and presently working as a PDF in the Department of Surgical and Gastroenterological Sciences, University of Padova, Padova, Italy in the project entitled
- Influence of conditioned medium of Myofibroblast on differentiation of cord blood derived stem cells.
- Expression and signal transduction pattern of microRNA155 in Inflammatory Bowel Disease and its associated colon carcinoma in human patients.
Techniques Familiar with During Research Work :
- Primary Cell Isolation and Culture (Stem Cell and Myofibroblast, Hepatic Stellate Cells, Buccal and Urothelial Cells, Lymphocyte and Spleenocytes).
- Culture of Cell Lines (A375. HepG2, Hela, CaCo2, HT 29, CMT 93)
- Cloning, Bacterial Culture.
- DNA and Total RNA and micro RNA isolation from tissues and cells, Agarose gel electrophoresis, RT-PCR.
- Real time-PCR.
- Gel electrophoresis (SDS-PAGE) of proteins.
- Western Blot Analysis of p53 and Bcl-2, ATF6, CHOP, PERK, Beta Actin, GAPDH, BIP, Cyclin D1, XBP, ERK-- Beta-catenin Proteins
- Autoradiography.
- Immunofluoroscence, Immuno-cytochemistry.
- ELISA
- Flowcytometry (FACs), Intracellular and Surface Staining of cells..
- Wound healing study, cell migration assay.
- Analytical Studies : Arsenic Estimation of Human Hair, Nail, Blood and Urine by Atomic Absorption Spectrophotometer (GBC, Avanta, Australia and Perkin Elmer, USA).
- Study of Metalloproteinase Activity by Gelatin Zymography.
- Somatic and meiotic chromosome aberration study of mice, Micronucleus testing, Mitotic Index, Sperm head anomaly study, study of NOR and C-banding patterns of mice chromosomes.
- Quantitative assay of proteins and enzymes (Acid phosphatase, alkaline phosphatase, alanine aminotransferase, aspartate amino transferase, reduced glutathione, lipid peroxidation, catalase, succinate dehyrogenase, glutathione reductase, gama GGT, Glucose-6-phosphate dehydrogenase).
- Determination of Antinuclear Antibody Titer (ANA), Scl-70 by ELISA Reader (ELDEX 3).
- Estimation of Glucose, total cholesterol content in blood of Mice and Human, serum hormone study (Estradiol, Testosterone, Cortisol), Hemoglobin Estimation, ESR and PCV Study from human and mice blood.
- Biological Sample Preparation for Scanning and Transmission Electron Microscopic studies and Observation of the sample.
- Animal Handling : Rearing and Maintenance of Mice and Rats.
- Instrument Handling :
- Real-Time PCR
- PCR
- Nano Drop, Thermo Scientific
- Western Blot Apparatus
- Atomic Absorption Spectrophotometer
- Flowcytometer (BD Biosciences)
- ELISA
- Spectrophotometer
- DNA Gel and SDS PAGE apparatus
- Gel-Doc
- Fluorescence and Phase Contrast Microscope
PAPERS PUBLISHED
2011
Khuda-Bukhsh AR, Banerjee A, Biswas SJ, Roy Karmakar S, Banerjee P, Pathak S, Guha B, Haque S, Das D, De A, Das D, Boujedaini N. First report on efficacy of a millesimal potency Arsenicum Album LM 0/3 ameliorating arsenic toxicity in human living in a high risk arsenic village- Zhong Xi Yi Jie He Xue Bao. 2011; 9 (6) :596-604).
2010
- Nai L, Scarpa M, Pathak S, Grillo AR, D'Incà R, Sturniolo GC, Castagliuolo I, Buda A. Intestinal Subepithelial Myofibroblasts of Ulcerative Colitis Patients Express Increased WNT5A Levels That Enhance Proliferation in an Autocrine Manner. Gastroenterology, Volume 138, Issue 5, Supplement 1, Pages S-791, May 2010
- Pathak S, Banerjee A, AR Khuda Bukhsh. Efficacy of Lycopodium Clavatum in reducing induced hepatotoxicity and genotoxicity in mice. Int Journal of Biological and Chemical Science 4(3) : 770-781, 2010
- P. Lamiki, J. Tsuchiya, S Pathak, R. Okura, U. Solimene, S. Jain, S. Kawakita, F. Marotta. Probiotics in diverticular disease of the colon : an open label study. Journal of Gastrointestinal and Liver Diseases 2010: 19 (1): 31-36.
- Mandal SK, Biswas R, Bhattacharyya SS, Paul S, Dutta S, Pathak S, Khuda-Bukhsh AR. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Eur J Pharmacol 2010; 626(2-3) :115-22.
- Banerjee A, Pathak S, Biswas SJ, Roy-Karmakar S, Naoual B, Belon P, Khuda-Bukhsh AR (2010). Comparative efficacy of two homeopathic potencies, Chelidonium Majus 30C and 200C, in amelioration of induced hepato-toxicity in rats. Homeopathy (2010) 99(3) :167-76.
2009
- Pathak S, Banerjee A, Paul S, Khuda-Bukhsh AR (2009). Protective potentials of a plant extract (Lycopodium clavatum) on mice chronically fed Hepato-carcinogens. Indian Journal of Experimental Biology Vol. 47, July 2009, pp. 602-607.
- Khuda-Bukhsh AR, Roy Karmakar S, Banerjee A, Banerjee P, Pathak S, Biswas SJ, Haque S, Das D, Boujedaini N, Belon P (2009). A follow-up study on the efficacy of the homeopathic remedy Arsenicum Album in volunteers living in high risk arsenic contaminated areas. Evidence-Based Complementary and Alternative Medicine 2009 Aug 24. [Epub ahead of print]
- Marotta F, Yadav H, Pathak S, Minelli E, Signorelli P, Lorenzetti A, Marandola P (2009). Inhibition of Human Breast Cancer Cell Growth and Enzymatic Activity by a Fermented Nutraceutical An In Vitro and In Vivo Study. Steroid Enzymes and Cancer : Ann. N.Y. Acad. Sci. 1155:273-7.
- Banerjee P, Bhattacharyya SS, Pathak S, Naoual B, Belon P and Khuda-Bukhsh A.R. (2009). On Evidences of Protective Potentials of Micro Doses of Ultra-High Diluted Arsenic Trioxide in Mice receiving repeated injections of Arsenic trioxide. Evidence-Based Complementary and Alternative Medicine (doi : 10/100/ecam/nen090).
- Pathak S, Roy Karmakar S, Banerjee A, Dutta S, Khuda-Bukhsh AR (2009). Combinational homeopathic therapy reduces Genotoxicity and Cytotoxicity in mice fed Carcinogens. Clinical and Experimental Homeopathy.1 :17-20.
2008
- Bhattacharyya SS, Mandal S, Biswas R, Paul S, Pathak S, Naoual B, Belon P, and Khuda-Bukhsh AR (2008). In vitro studies demonstrated anticancer activity of an alkaloid of the plant Gelsemium sempervirens. Experimental Biology and Medicine 233(12) :1591-601.
- Metugriachuk Y, Tsuchiya J, Marotta F, Kuroi O, Kawakita S, Pathak S, Minelli E (2008). Open label randomized trail on the effectiveness of a herbal compound in selected patients affected by functional dyspepsia. International Medical Journal 15(1), 47-51.
- Banerjee P, Bhattacharya SS, Bhattacharjee N, Pathak S, Boujedaini Naoual, Belon P, Khuda Bukhsh AR (2008). Ascorbic acid combats arsenic-induced oxidative stress in mince liver. Ecotoxicology and Environmental Safety. Doi :10.1016/jecoenv.2008.07.005. Aug 18 [Epub ahead of print].
- Banerjee P, Bhattacharjee SS, Pathak S, Belon P, Khuda-Bukhsh A.R (2008). Comparative efficacies of microdoses of a potentized homeopathic drug, Arsenicum Album in amelioration of toxicity induced by repeated sub-lethal injections of Arsenic trioxide in mice. Pathobiology, 75(3) :156-70.
- Khuda-Bukhsh A.R, Pathak S (2008). Homeopathic Drug Discovery: Theory update and Methodological aspect. Expert Opinion in Drug Discovery, 3(8):979-900.
- Banerjee A, Biswas R, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh A.R. (2008). Crude Turmeric extract reduces oxidative stress in rats chronically fed carcinogens: An assessment of its hepatoprotective role in a time course study. Journal of complementary and Integrative Medicine (Vol. 5: Iss. 1, Article 34.).
2007
- Pathak S, Bhattacharjee N, Das JK, Choudhury SC, Roy-Karmakar S , Banerjee P, Paul S, Banerjee A, Khuda-Bukhsh AR (2007). Supportive evidences for anti-cancerous potential of an alternative medicine in hepatocarcinogenesis of mice, Research in Complementary Medicine (Forsch Komplementarmed), 14:148-156.
- Bhattacharjee N, Pathak S, Khuda-Bukhsh A.R (2007). Amelioration of Carcinogen Induced Toxicity in Mice by Administration of a Potentized Homeopathic Drug, Natrum Sulphuricum 200. Evidence based Complementary & Alternative medicine 1-11 DOI:10.1093/ecam/nem067.
- Pathak S, Khuda-Bukhsh A.R. (2007). Assessment of hepatocellular damage and hematological alterations in mice chronically fed p-dimethyl aminoazobenzene and phenobarbital. Experimental and Molecular Pathology 83, 104-111.
- Belon P, Banerjee A, Roy Karmakar S, Biswas SJ, Chaki Choudhury S, Banerjee P, Das JK, Pathak S, Guha B, Paul S, Bhattacharjee N and Khuda-Bukhsh A.R. (2007). Homeopathic remedy for arsenic toxicity. Evidence-based findings from a randomized placebo controlled double blind human trial. Science of the Total Environment, 384: 141–150.
- Khuda-Bukhsh AR, Belon P, Biswas SJ, Roy-Karmakar S, Banerjee P, Banerjee A, Guha B, Das JK, Pathak S, Choudhury SC, Bhattacharjee N (2007). Is An Elevated Antinuclear Antibody Titer In Subjects Living In Two Groundwater Arsenic Contaminated Villages Indicative of a Time-Dependent Effect Of Arsenic Exposure- Environmental Science: An Indian Journal, 2(1):1-8. http://esaij.tsijournals.com/ESVol2Iss1.htm
2006
- Pathak S, Das JK, Biswas SJ, Khuda-Bukhsh AR (2006). Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azodye induced hepatocarcinogenesis in mice. Molecular and Cellular Biochemistry. 285(1-2):121-31.
- Belon P, Banerjee P, Chaki Choudhury S, Banerjee A, Biswas SJ, Roy Karmakar S, Pathak S, Guha B, Chatterjee S, Bhattacharjee N, Das JK and Khuda-Bukhsh AR (2006). Can administration of potentized homeopathic remedy, Arsenicum Album, alter anti-nuclear antibody (ANA) titer in people living in high risk arsenic contaminated areas- : I. A correlation with certain hematological parameters. Evidence-Based Complementary and Alternative Medicine 3(1): 99–107.
2005
- Khuda-Bukhsh AR, Pathak S, Guha B, Roy-Karmakar S Das JK, Banerjee P, Biswas SJ, Mukherjee P, Bhattacharjee N, Choudhury SC, Banerjee A, Bhadra S, Mallick P, Chakraborti Mallick J, and Mondal B (2005). Can homeopathic arsenic remedy combat arsenic poisoning in human exposed to groundwater arsenic contamination- a preliminary report on first human trial. Evidence-Based Complementary and Alternative Medicine; 2 (4): 537–548.
- Biswas SJ, Pathak S, Bhattacharjee N, Das JK and Khuda-Bukhsh AR (2005). Efficacy of a potentized homeopathic drug, Carcinosin-200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-DAB induced Hepatocarcinogenesis in mice. Journal of Alternative and Complementary Medicine. Mary Ann Liebert Pub Volume 11, Number 5, 2005, pp. 839–854. © Mary Ann Liebert, Inc.
2004
- Biswas SJ, Pathak S and Khuda-Bukhsh AR (2003). Assessment of genotoxic and cytotoxic potentials of an anti-epileptic drug, Phenobarbital, in mice: a time course study. Mutation Research 563(2004) 1-11.
SEMINARS ATTENDED
- Pathak S, Nai L, Grillo A, Brun P, D'Incà R, Sturniolo GC, Castagliuolo I, Buda A (2009). Towards understanding the possible role of microRNAs in ulcerative colitis: An experimental approach (In IV Annual meeting of IG-IBD, Bologna, Italy, 13-14th Nov, 2009).
- Nai L, Grillo A, Scarpa M, Pathak S, D'Incà R, Sturniolo GC, Castagliuolo I, Buda A (2009). Sub-epithelial Myofibroblasts in patients with high levels RCU express Wnt 5a: influence on cell proliferation through an autocrine mechanism. In IV Annual meeting of IG-IBD, Bologna, Italy, 13-14th Nov, 2009).
- Pathak S and Khuda-Bukhsh A.R (2007). Homeopathy– Myth or a New Art of Treatment- National Symposium on 21st Century Research in Biochemistry and Biophysics February 1st to 3rd 2007 at University of Kalyani, Department of Biochemistry and Biophysics.
- Pathak S and Khuda-Bukhsh A.R. (2006). Evaluation of Cytogenetical and Biochemical Alterations in Mice Chronically Fed p-dimethylaminoazobenzene and Phenobarbital. National Symposium Cross-talk between Zoology and Technology Nov. 16-17, 2006 at University of North Bengal, Department of Zoology.
- Biswas SJ, Pathak S and Khuda-Bukhsh A.R. (2003) Cytogenetic, enzymatic and electron microscopic studies reveal genotoxic potentials of an antiepileptic drug, Phenobarbital. National Seminar on Recent Advances in Stress Physiology, Toxicology and Immunology, University of Kalyani, Nov. 27-28, 2003.
Submitted PAPERS
2011
- Pathak S, Banerjee A, Dutta S, Khuda-Bukhsh AR (2011). Is chronic feeding of low dose alcohol hepatotoxic or genotoxic- : A time course study in mice. (Communicated).
- Pathak S, Bhattacharya N, Banerjee A, Dutta S, Paul S and Khuda-Bukhsh AR (2011) Further evidences for anti-hepatocarcinogenic potentials of Lycopodium-30 in mice. Journal of Central Council for Research in Homeopathy (Communicated).
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Date & Time : 15th Jul 2011 9:02 AM (UTC)
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