www.ibsd-imphal.nic.in Recruitment 2011 Institute of Bioresources and Sustainable Development : Scientist

[muthukalee]

Government of India
Department of Biotechnology
ADVERTISEMENT No. 01/2011
Imphal, the 20th April, 2011

The Institute of Bioresources and Sustainable Development (IBSD) is one of the autonomous institutes under the Department of Biotechnology, Ministry of Science & Technology, Govt. of India. The objective of IBSD is to develop and utilize the rich bioresources of the Northeastern Region of the country through the application of modern tools of biology and biotechnology. Currently the Institute has its Headquarters in Imphal, Manipur and a Regional Centre in Gangtok, Sikkim. The institute invites application for the following posts in its Headquarters at Imphal and Regional Centre at Gangtok :

Post No.1 : One Scientist – E: (Plant Biotechnology/Plant Molecular Biology) in the scale of pay of Rs. 37400-67000+GP 8700
Post No.2 : One Scientist – E: (Natural Product Chemistry) in the scale of pay of Rs. 37400- 67000+GP 8700
Post No.3 : One Scientist – E: (Aquaculture) in the scale of pay of Rs. 37400-67000+GP 8700
Post No.4 : One Scientist – C: (Natural Product Chemistry) in the scale of pay of Rs. 15600- 39100+GP 6600
Post No.5 : One Scientist – C: (Economic Entomology) in the scale of pay of Rs. 15600-39100+GP 6600
Post No. 6 : One Stores and Purchase Officer (on contractual basis)

POSTS IN REGIONAL CENTRE OF IBSD AT GANGTOK, SIKKIM
The IBSD has recently established its Regional Centre in Gangtok, Sikkim with an aim of sustainable development and utilization of bioresources of the Eastern Himalayas including generation of appropriate technology packages leading to development of bio-enterprises in the region. The institute invites applications for the following contractual positions in its Regional Centre in Gangtok, Sikkim :

Post No.1 : One Scientist – (Plant Bioresources)
Salary Structure : Rs. 48,000/- p.m. (Consolidated)
Post No. 2 : One Scientist – (Microbial Resources)
Salary Structure : Rs. 30,000/- p.m. (Consolidated)
Post No. 3 : One Administrative Officer
Salary Structure : Rs. 25,000/- p.m. (Consolidated)

General Conditions :
Applicants should be Indian nationals
The maximum age limits for the following positions will be as follows :
IBSD Headquarters at Imphal, Manipur :
Scientist-E : 55 years
Scientist-C : 35 years
Senior Accounts Officer : 35 years
Store & Purchase Officer : 40 years
IBSD Regional Centre at Gangtok, Sikkim :
Post 1 : 50 years
Post 2 : 35 years
Post 3 : 40 years

Completed applications strictly in the "FORMAT OF APPLCATION" and a recent passport size photograph fixed at space shown in the format along with attested copies of all mark sheets, caste certificate, experience certificates, etc. together with a non-refundable fee of Rupees fifty only (PH/SC/ST candidates are exempted from the payment of application fee) payable in form of cross Demand Draft/IPO in favour of Director, IBSD, Imphal should reach the Director, Institute of Bioresources and Sustainable Development, Takyelpat Institutional Area, Imphal- 795001, Manipur on or before 10th June (Friday), 2011.

The candidates must send a soft copy of the duly filled in application (without testimonials) to the email : nayan.ibsd@nic.in, director.ibsd@nic.in

The candidate must clearly write on the top of the envelope, Advt. no, Post applied, and the place (IBSD Headquarters or RCIBSD) of post.

More Details : http://www.ibsd-imphal.nic.in/jobs/A...ERTISEMENT.pdf

[Guest-IJT]

Renjith M
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The submitted value of field named "Email :" is:
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renjithmahasenan AT gmail.com
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The submitted value of field named "Designation / Name of the Post / Skill Set :" is:
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Scientist
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The submitted value of field named "Your Cover Letter :" is:
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Dear Sir/Madam,
I am submitting the enclosed resume for consideration of a position in Research and Developement, My background has given me the hands on experience in all facets of invitro biochemical assays and cell culture based assays in the field of anti-obesity , anti-diabetic, anti-inflammatory , anti-cancer, skin lightening, anti-oxidant studies, cyto-toxicity assays , Experience includes study designing, validation and interpretation of research results. Other responsibilities included preparation of SOP, review of SOPs and report format according to ISO IEC 17025, supervise project trainees. Hands on experience in assays such as Adipogenesis inhibition assay in 3T3 L1 cell lines, Reactive Oxygen Species (ROS) scavenging in cell lines, Melanin inhibition in B16F1 mouse melanoma cell lines, Melanin enhancement in B16F1 mouse melanoma cell lines, UV protection ( A&B) in fibroblast and keratinocyte cell lines, Cell proliferation studies, DPPH radical scavenging activity, Oxygen Radical Absorbance Capacity (ORAC), Hydroxyl Radical Averting Capacity (HORAC), NO radical scavenging, Mushroom Tyrosinase inhibition, Inhibition of Hyaluronidase, DPPIV inhibition, Inhibition of a glucosidase, inhibition of Collagenase, inhibition of Elastase, Inhibition of amylase, Cyto-toxicity studies in cell lines , Activity assay of protease, lipase, cellulase ,amylase and Microbiology techniques such as pathogen testing , microbial load testing, Bacterial Reverse Mutational Assay(AMES TEST), Pathogen testing, Total microbial count, Total yeast and mold count etc. that would contribute to your organization’s goals and objectives. Currently I am working as Jr Scientist in SAMI LABS LTD, at Bangalore, India, since 2007, completed my Master Of Science in Biotechnology I am enthusiastic about exploring opportunities with your esteemed organization, if my resume is suitable for the post, you can schedule an interview at your convenience.
Thank you for your consideration,
Sincerely
Renjith Mahasenan
Current Location - Bangalore
Current Designation – Jr. Scientist
Experience – 4 Years
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The submitted value of field named "Copy Paste Your CV / Resume Here :" is:
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RENJITH. M
M.Sc. Biotechnology
renjithmahasenan AT gmail.com
CAREER OBJECTIVE :
To fulfill my everlasting quest and ambitions in the field of biotechnology with my dedication, hardwork, luck, and God’s grace, to pave the way for building up my knowledge assets for the development of team and an organization. Quest to work in a professional environment, which will enable me to develop my potentiality and efficiency, also to meet the challenges and excellence in the field.
CORE RESEARCH AREA :
Research experience includes invitro and cell culture based biochemical assays in the field of obesity, cancer, diabetes, anti-inflammatory, skin lightening, anti- oxidant studies. Experience includes study designing, validation and interpretation of research results. Other responsibilities included preparation of SOP, review of SOPs and report format according to ISO IEC 17025, supervise project trainees. Hands on experience in assays such as Adipogenesis inhibition assay in swiss 3T3 L1 (pre adipocytes) cell lines, Apoptosis, Reactive Oxygen Species (ROS) scavenging in swiss 3t3 cell lines, Melanin inhibition and enhancement in B16F1 mouse melanoma cell lines, UV protection ( A&B) in fibroblast and keratinocyte cell lines, apoptotic studies in HeLa cell lines, Cell proliferation studies, DPPH radical scavenging activity, Oxygen Radical Absorbance Capacity (ORAC), Hydroxyl Radical Averting Capacity (HORAC), 11Beta HSD inhibition, TNF-a inhibition, PGE2 inhibition, LTB4 inhibition, Nitric Oxide radical scavenging, Mushroom Tyrosinase inhibition, Inhibition of Hyaluronidase, DPPIV inhibition, Inhibition of a glucosidase, inhibition of Collagenase, inhibition of Elastase, Inhibition of amylase, Cyto-toxicity studies in cell lines, Activity assay of protease, lipase, cellulase ,amylase and Microbiology techniques such as pathogen testing , microbial load testing, Bacterial Reverse Mutational Assay(AMES TEST) etc.,
TECHNICAL KNOWLEDGE :
Animal and human cell culture , Micro plate reader, Flow cytometry, UV Spectrophotometer ,TUNEL Assay, MTT Assay , Electrophoresis Techniques, RT PCR, etc.
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RESEARCH EXPERIENCE :
May 2007 - till present :
Jr. Scientist-
SAMI Labs Ltd
Corporate R & D Unit, Peenya, Bangalore, India
Experience in the Standardiing invitro methodologies and implementation of NABL Guidelines : Study design, analysis, Validation, assay developement and interpretation of research results. (Cardiovascular, Diabetes, Obesity, Antioxidant, Inflammatory, and cosmetic) ,Preparing SOPs. Review to approve new SOPs and report format according to NABL guidelines. Supervise Project Trainee and coordinating the following projects-
Models to determine Antioxidant potential- Antioxidants stop the free radical formation or interrupt an oxidizing chain reaction and minimize the damage caused by the free radicals. Reduced exposure to free radicals and increased intake of antioxidant nutrients has the potential to reduce the risk of free radical-related health problems.
1. DPPH radical scavenging activity – for total free radicals
2. ORAC – for peroxyl radicals
3. HORAC- for hydroxyl radical
Models for skin lightening : MITF activation ultimately results in increased tyrosinase expression and melanogenesis via tyrosinase gene activation.
1. Inhibition of Tyrosinase : Tyrosinase is the enzyme that catalyzes the production of melanin.
2. Inhibition of Melanocyte stimulating hormone (MSH) induced Melanogenesis..
3. UV protection : UV protection in Swiss 3T3 fibroblast and HaCaT keratinocyte cells.
Models to determine Anti ageing potential : Inconsiderate overstay of inflammation is associated with chronic diseases such as arthritis, heart diseases, atherosclerosis, Alzeimer’s disease, Type 2 diabetes etc. Inflammatory responses in the skin caused due to UV exposure, pollution etc., fasten the process of ageing. Anti inflammatory drugs counteract inflammation.
1. Anti Hyaluronidase activity
2. Anti Collagenase activity
3. Anti Elastase activity
Models for anti cellulite : Cellulite results due to enhanced adipogenesis which results in the accumulation of chunks of adipocytes under the skin dermis. Cellulite control ultimately is due to the net reduction in adipose tissue.
1. Inhibition of adipogenesis. (3t3L1 Cell lines)
2. Stimulation of lipolysis. (3t3L1 Cell lines)
3. Glycerol estimation
4. CETP inhibition
5. Anti Lipase inhibition
Models for anti diabetes :
1. DPP IV Inhibition assay : inhibition of DPP IV enzyme to production of Glucagon-like peptide-1 (GLP-1) and gastric inhibitor peptide (GIP)
2. Alpha glucosidase Inhibition assay
3. TNF a inhibition assay
4. PGE2 Inhibition
5. VEGF Inhibition
Models for Cytotoxicity study : for determining the effect on cell survival using SRB, MTT and NRU method.
Experience in working with ELISA based methods.(LTB 4, PGE2, VEGF, TNFa etc)
Experience in microbiology :
1. Screening of pathogens, such as
- Escherichia Coli
- Pseudomonas aeruginosa
- Staphylococcus aureus
- salmonella
2. Test for Total Coliforms---
3. Test for Yeast and Mold--
4. Test for Total Microbial Count--
5. AMES Test
Activity checking of the Digestive Enzymes in the patented product DigeZymes by biochemical methods.
1. a amylase activity : To check the activity of amylase enzyme responsible for hydrolyse dietary starch into di and tri saccharides
2. Anti a amylase activity : To check the activity of sample whether it can inhibit amylase enzyme or not for the treatment of diabetes
3. Anti Lipase activity : For the inhibition of lipase enzymes responsible for the digestion, transport and processing of dietary lipids
4. Lactase activity : To check the activity of lactase enzyme responsible hydrolyzing of disaccharide lactose into galactose and glucose monomers ( hydrolyzing of O-Nitrophenyl-ß-Galactopyranoside)
5. Neutral protease activity : To check the activity of hydrolysis of proteins(casein) by the break down of peptide bonds to liberate amino acids
6. Cellulase activity : assay based on the cellulytic hydrolysis of Carboxy Methyl Cellulase to reducing sugar
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ACADEMIC CREDENTIALS:
- M.Sc. (2005): Specialization in Biotechnology from Muthayammal College of Arts and Science, Periyar University, Salem, Tamilnadu (2003-2005).
- B.Sc. (2003): Zoology, Botany, Chemistry, From M.S.M College, Kerala University(2000-2003)
Course modules: : Cell Biology, Microbiology, Biochemistry, Plant Biotechnology, Plant Molecular Biology, Immunology, Molecular Biology, Animal Biotechnology, Bioprocess Technology, Enzymology and Enzyme Technology, Genetic Engineering (GE), Bioinformatics, Environmental Biotechnology, Intellectual Property Rights(IPR).
Title of the Projects:
Worked on a project in Cancer research during November 2004 to March 2005 at Regional Cancer Center, Trivandrum
1. Worked in a project titled ’"MOLECULAR ELUCIDATION OF ANTITUMOR PROPERTIES OF BENZAMIDE RIBOSIDE AGAINST CERVICAL CANCER’ at Regional Cancer Center Trivandrum, Kerala as a part of MSc Biotechnology course under the guidance of Dr.M.Radhakrishna Pillai.
In this study, the anti tumor activity of Benzamide Riboside against cervical cancer, at the cellular and molecular level against the HPV infection in established cell lines(HeLa,). were analyzed. HeLa cells responded better to the lower concentrations of Benzamide Riboside as evidenced by TUNEL staining. Acridine orange/Ethidium bromide staining showed that Hela cells exhibit cell shrinkage or chromatin condensation at lower concentration. RT-PCR results showed that Benzamide Riboside induced growth inhibition in HPV- positive cervical carcinoma cells. This has an advantage more than the other cancer cells due to the additional anti viral activity, i.e. Benzamide Riboside-dependent down regulation of E6/E7 expression.
2. “CHEMICAL AND MICROBIOLOGICAL ANALYSIS OF FOOD AND WATER”, under the guidance of Dr C.K NAIR at Cashew Exporting Promoting Council, Kollam.”
Electrophoresis Techniques and its procedure- 2D gel electrophoresis, SDS Page, Agarose gel electrophoresis, Immuno diffusion electrophoresis, Rocket immuno electrophoresis etc at BIOTECH, YERCAUD, SALEM
3. To study the working principle & procedure of PCR
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SKILL
1. Screening of Natural compounds (Phytochemicals) and synthetic analogs for their ability to inhibit enzymes and to understand the mechanism of mutagenitic, antidiabetic, anti obesity, antioxidant and anti-inflammatory action.
2. Developed, standardized and validated assays in accordance with NABL-ISO-2005 guidelines.
3. Experience in working with a variety of cells (Human and Animal cells) for Nutraceutical, and cosmetic applications.
4. Trouble shooting any problems that may arise during normal laboratory operations.
5. Evaluate experimental results, maintaining records, analyze and interpret data (using Excel , Graph Pad etc),
CELLS:
1. Cryopreservation, subculture and maintenance of cells like, HaCaT, HepG2, swiss 3T3, B16F1, Swiss 3T3 L1, etc.
2. Performed antidiabetic, anti-inflammatory, antioxidative, bioassays in different type of cells.
INSTRUMENTS:
1. Handling of microplate reader (Fluostar) and UV spectrophotometer for bioassays and Minolta for Brightness activity.

COMPUTER:
1. Windows 2000/ XP, MS Office, Power Point, MS Excel
2. Statistical Tools - Excel and Graph Pad, Minolta.
HOBBIES: Meditation, Reading, Observation, Badminton, Cricket, Swimming, Body building, Painting, Sound dubbing.

Email:sarangbani AT samilabs.com
Declaration:
I hereby declare that the information furnished above is true to the best of my knowledge and I, myself, will be responsible if any of the information is found to be wrong.
Renjith M
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More Information about this submission and submitter:-
___________________________________________________
Submission ID : 4147107
Date & Time : 18th May 2011 2:10 PM (UTC)
IP Address : 117.231.113.14
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