www.synchronresearch.com Synchron Research Services Pvt Ltd Ahmedabad : BioAnalytical Scientist

[muthukalee]

1. Designation : Scientist

2. Department : Bio Analytical

3. No. of vacancy : 2

4. Qualification : M.Sc-Chemistry (any stream)

5. Experience : 2 years and more, in the Bioanalytical department of CRO (BABE Operations), should be capable of handling LCMS, HPLC ETC

6. Location: Ahmedabad.

Interested candidates may send in their CV's on hr@synchronresearch.com

About us:
Synchron is a leading contract research organization in India, designed to meet the specific requirements of the clients in the field of :
» Clinical registration of new pharmaceutical products and medical devices, from phase I to phase IV, including Bioequivalence, Bioavailability, Pharmacokinetic / Pharmacodynamic studies, Statistical Analysis and Data Management strictly adhering to ICH and GCP guidelines.
» The company offers competitive and high quality clinical trial services to domestic and international pharmaceutical and Bio-Pharmaceutical companies.

Contact us:
Synchron Research Services Pvt Ltd
"The Chambers", 3rd Floor
Sarkhej-Gandhinagar Highway,
Bodakdev, Ahmedabad - 380 054

http://www.synchronresearch.com/

[chemcontect]

Dear Sir,
Good morning.
Hope you are well.
My self Panchal Jigar, working as research scientist-II in oxygen bio research pvt ltd.
In have 6.0 yrs of basic research experience of R&D, I am very proficient to synthesis new molecules and also have good experience of scale up in bulk scale. I have also one year of experience to lead team as a project leader.
Please find attached file of my updated CV and consider it for a position in synthetic R&D.
Kindly let me know, If you have any comments or queries.
Kind Regards,
Panchal Jigar N,
Research Scientist-II,
Oxygen Bio Research Pvt Ltd,
Ahmedabad.

CURRICULUM VITAE
Objective :
Seeking a professional challenging career in an organization that utilizes my skill and ability in
R&D Department and supporting the team to achieve higher standards of performance.
Key skills :
R&D background, Experience of API R&D and CRO R&D, Good Knowledge of practical chemistry and
trouble shooting, good communications skills, Good interactions to the ADL, QA and QC department,
Good leaderships and team management skills.
Vocational Experience :
Total Experience : 6.0 yrs experience as Research Scientist in Synthetic chemistry.
Present Employer :
Oxygen Healthcare Research Pvt. Ltd, Ahmadabad (Gujarat)
Job Title : Research Scientist, Duration: 10 Nov 2008 - till date
Company Profile : Oxygen healthcare is Growing CRO in India providing medicinal chemistry input to
hit-to-lead and lead optimization projects as well as at the pre-clinical developmental stage.
Previous Employers :
Jubilant Chemsys Ltd, Noida (NCR)
Job Title : Research Associate, Duration: 20 Aug 2007 to 8 Oct 2008
Company Profile : Jubilant Chemsys Ltd is largest CRO in India providing medicinal chemistry services
for global pharmaceutical and biotech industries.
Dishman Pharmaceuticals and chemical Ltd Ahmadabad (Gujarat)
Job Title : Research chemist. Duration: 1 June 2005 to 13 Aug 2007
Company Profile : Dishman Pharmaceuticals and chemical Ltd is leading pharmaceutical company in
India with strong R&D pipe-line, involved in APIs (active pharmaceutical ingredients, custom synthesis,
and Contract manufacturing services), Drug intermediates, and fine chemicals.

- Participate in international seminar on Recent Development in structure and ligand based Drug
Design by Schrödinger on 23 rd
December 2009 at Department of Chemistry, Saurashtra
University, Rajkot- 360 005, Gujarat, India.
- Attended 15 ISCB Indian society of chemists and biologists) conference on 4-7th February 2011
th by ISCB at Rajkot- 360 005, Gujarat, India.
Academic Profile :
- Post Graduate with organic chemistry from Gujarat University, (54.44%, Year 2005).
- Graduate with chemistry from Gujarat University, (64.85%, Year 2003).
Computer Proficiency :
- Advance Diploma in Computer Application (Packages known : Windows 2000, Corel Draw 11,
Adobe Photoshop 7.0, Adobe PageMaker 6.5 and MS Office 2000.
- Chem-Draw, Chem-Sketch, Marvin-Sketch, ISIS Draw etc.
Languages :
- English : Excellent written and oral skills.
- Hindi : Excellent written and oral skills.
- Gujarati : Excellent written and oral skills.
- Marathi : Little understanding.
Job Responsibilities :
- Excellent team management skills with one year of team management experience.
- Well versatile with Literature survey, familiar with search engines like Bail- stein, Scifinder and
Reaxys.
- Developing novel synthetic route and process Development.
- Scale up and process development from bench work to Kg scale
- Working experience on full time Medicinal Chemistry projects of reputed global pharma
companies and made no. Of library compounds.
- Planning and conducting all Laboratory Experiment
- Primary analysis on thin layer chromatography
- Purification of compounds by extraction, column chromatography (gravity and flash), vacuum
distillation, Recrystallisation etc
- Interpretation of molecule by NMR, Mass, LCMS, IR, HPLC, GC etc.
- Well co-ordination with team member and maintaining accurate record of research activity.
Industrial work experiences :
- Asymmetric synthesis
- Experience in Basic Research & Microwave synthesis.
- Experience in protecting And Deprotecting chemistry.
- Few Experience on chemical resolution and enzymatic chemistry.
- Synthesis of organic compounds in multiple reactions.
- Experience in handling milligrams level reactions, also able to handle Grams & Kilograms
Reaction.
- Extend needy support to production department on new process implementation.
- Handling of different moisture sensitive reagents.
- Able to transfer Lab Scale Reaction to pilot plant or Plant.
- Able to Communicate with Q.C & Q.A.
Vocational Training :

Instruments Handling :
- Rotary evaporators
- Parr hydrogenator, autoclaves
- Preparative TLC instrument
- Simple and Flash column chromatography.
- Combi-Flash
- Micro wave
- PH-meter
- Gas station
- Gen vac
- Relay for parallel Synthesis
Specific Reaction Done :
Buchwald Coupling, Friedal Craft reaction, Strecker reaction, Fries rearrangement, Hydrogenation
Reaction, Halogenations, Reductive Amination, Hoffman Reaction, Swern Oxidation, Suzuki Reaction,
Witting Reaction, Stile Coupling, Sonogashira Reaction etc…
Reagent Handled:
LAH, NaH, Pd/C, Pt/c, NaCN, Tetra kis, different Pd, Fe , Cu catalysts, Raney Nickel, DCC, CBZ-Cl,
Boc anhydride,BuLi,t-BuLi, LDA,AlCl3, Na metal, NBS, sodium borohydride, PCl5, Co2Cl2, PoCl3,
Phosgene gas or Solution, hydrogen, isobutylene, Pyridinium dichromate, Iridium catalyst etc….
Strengths:
- Result Oriented & Optimistic.
- Good observations skills.
- Self motivated.

[Guest]

Dipak S Harwani

Email : dharwani AT gmail.com
Dear Sir/Madam,
I am writing to express my interest in securing employment, as you will see. I come to you with a background that you will find unique and distinctive among your typical applicants. Over the past 5+ years, I have established myself as highly successful Bioanalytical Scientist. While rewarding, I am ready for new challenges and opportunities.
If you are seeking :
Study sample analysis supervisor
I come to you with :
Great efficiency of Review Raw data and Chromatograms
If you are seeking :
Speedy Method development talent
I come to you with :
Good level of Experience, Chemistry Knowledge and logics on different extraction method like SPE, LLE, PPT as well as good knowledge about chromatography
If you are seeking :
Instrument operator
I come to you with :
Great efficiency of handling SCIEX instruments like API-2000, API-3000, API-3200,API-4000,API-5000
If you are seeking :
Different Country submissions
I come to you with :
Knowledge about submission to four regulatory authorities
i.e. USFDA, EUROPE(EMEA), ANVISA, CANADA
The Qualification outlined above are representative of the value I offer and are fully outlined in the enclosed resume. I am confident that I would quickly become a contributing team member. Should you agree, I would welcome a chance for an interview.
SYNOPSIS
Enjoy challenging jobs, meeting deadlines and working in any environment, with a strong interpersonal skills, analytical approach and flexible nature. Believe in efforts till success.
CAREER OBJECTIVE
To work with a progressive organization involved in Research and development in which I can contribute my skills to enhance my own productivity at the same time achieving the organizational objectives with the attribute of time, quality and discipline.
ACADEMIC INFORMATION
- Master in Chemistry from School of Science, with aggregate of 59%, Gujarat University, Gujarat in July 2005
- B.Sc. (Chemistry) with 66% from S.P.T Sci. & Arts College, Gujarat University, Gujarat in May 2003.
- HSC with 53% from GSEB, GandhiNagar, Gujarat, in July, 2000
- SSC with 57% from GSEB, GandhiNagar, Gujarat , in April, 1997

PERSONAL DETAILS
CURRENT EMPLOYMENT
Organization : Sun Pharmaceutical industries Ltd.
Department : Bioanalytical Research
Designation : Group leader
Date of Joining : 05 Jun 2006
Job Responsibilities : - Working as Research Officer
- Project management of the assigned project(s), data review, calibration and maintenance of equipment(s)
- Supervision of general laboratory activities and contingency arrangements
- SOP, report preparation and reply to relevant quality assurance queries
- Guide and supervise analyst(s) for the assigned activities
- Leading a group in carrying out BA/BE analysis using LC-MS/MS systems.
- Operation, maintenance and periodical calibration of LC-MS/MS systems.
- Bioanalytical method Development, Validation and subsequent biosample analysis using LC-MS/MS with complete adherence to the ANVISA, US FDA, EMEA and GLP guidelines.
- Designing of Bioanalytical Protocols and SOP`s.
- Documentation of the bioanalytcal studies and projects.
- Troubleshoot critical bioanalytical issues/bottlenecks and support DMPK team in the areas of :
1. Reliability and quality of analytical data
2. Laboratory automation
3. Maintenance and calibration of laboratory instrumentation
4. Method development for different biological matrix.
PREVIOUS EMPLOYMENT
Organization : Lambda Therapeutic Research Ltd..
Department : Bioanalytical Research
Designation : Sn.Research Associates
Date of Joining : 08 Aug 2005
Job Responsibilities : - Working as Research assistant
- Documentation : Online Raw Data Recording, Chromatographic Data Generation, Log book Recording, Reconciliation of Raw Data Forms and Method Book Writing.
- Sample Processing using Liquid-Liquid Extraction, Protein Precipitation and Solid Phase Extraction Techniques.
- Software Application : analyst 1.3.1,1.4,1.4.1,1.4.2
- Instrumentation : LC-MS/MS (API 2000, API 3000, API 4000, API 3200 of MDS Sciex) ( LC of Shimadzu, perkin-Elmer & Agilent),
- Method Validation, Method Development, Bioanalysis of drug for clinical studies for Bioequivalence and Bioavailability in Bioanalytical Laboratory.
- Routine maintenance of LC/MS/MS and HPLC system
- Documentation and implementation of GLP System.
- Extraction of drug from different matrix by SPE, LIQUID-LIQUID EXTRATCTION and PRECIPITATION.
- Accurately record methods and the results in study documentation.
- Understanding the scientific basis of techniques being used for bioanalysis.
- Updating Technical details on LC/MS/MS (Methodology and Trouble shooting )
- Guide and supervise analyst(s) for the assigned activities

TRAINING :
- Basic Operator training course on LC/MS/MS including Calibration held at state of art Genomics & Proteomics Training Facility at Gurgaon, India.

Job Responsibilities
- MD and MV of generic and NCE molecules
- Project handling
- Assigning resources for project
- Checking the compliance of relevant checklist
- Managing inventory
- Tracking the progress and completion of project (s)
- Tracking the delivery of reports from time to time
- Maintaining the equipments – Major and minor both
- Calibration and maintenance of equipments
- Maintaining the equipment log (s)
- Review Bioanalytical data
- Preparation and review of SOPs, Method SOPs, Protocols, Plans and Reports
- Reply to relevant BQM,/QA queries in co-ordination with team members/BQM respectively
- Execution and maintenance of GLP, GCP, Safety and Quality systems
- Responsible to update the Sr. group leader on progress of projects on daily basis
- Responsible for training and up gradation of group members and maintaining the training records
- Responsible to archive the relevant data
- Responsible to present 1-2 presentations and publish at least 1 research paper
- Responsible to appraise group/team members
AUDIT FACED :-
- EUROPE AUDIT AT SUN PHARMACEUTICAL INDUSTRIES LTD IN MAY 2009.
- ANVISA AUDIT AT SUN PHARMACEUTICAL INDUSTRIES LTD IN DECEMBER 2009.
- USFDA AUDIT AT SUN PHARMACEUTICAL INDUSTRIES LTD IN APRIL 2010.
SELF - APPRIASAL:
Honesty is what I breathe, Dedication is what I give and working for a common goal is what I live for. Nothing is more important to me then honestly working for what I dedicated myself to.

[Guest]

SAPTARSHI MOITRA
E-mail : Saptarshi.moitra AT yahoo.com
Objective :
To secure a position in a learning environment where I can effectively gain my knowledge and continue to develop myself as a successful person by absorbing the culture of the organization.

Educational Qualifications :
Exam Passed Institute University Year of passing Grade
M.Pharm
(Master in pharmaceutical chemistry) Gupta College of technological sciences, Asansol.
WBUT
2011
8.79
Exam Passed Institute University Year of passing Grade
B.Pharm
(Bachelor in pharmacy) Gupta College of technological sciences, Asansol.
WBUT
2009
7.96
Exam Passed Institute Council Year of passing Marks
Higher Secondary
(XII th) Aryya Vidya Pith W.B.C.H.S.E 2005 67.8%
Secondary
(X th) Aryya Vidya Pith W.B.B.S.E 2003 81.8%
Industrial Training :

One month’s summer training from BROOK’S LABORATORIES, Baddi, H.P., India.
Project :
Thesis submitted under the guidance of Mr. Manabendra Dhua, Asst. Professor, Department of Pharmaceutical Sciences, Gupta College of Technological sciences, Ashram More, Asansol-01 on : “STABILITY INDICATING RP HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE ANALYSIS OF GLIBENCLAMIDE BULK AND ITS TABLET FORMULATION”

Seminars Attended :
1. Seminar on “QUALITY CONTROL and QUALITY ASSURANCE” by P.P. Sharma (Ex-Deputy Drug Controller, Delhi, India) and Arabindakshya Mishra (Associate Director of Development Quality Assurance, DR. REDDY’S LABORATORIES LTD.)
2. Seminar on “PHARMACEUTICAL PRODUCT DEVELOPMENT” by Adnan Sabir, Head Consultant, DR. REDDY’S LABORATORIES LTD.

Instrumental Exposure :

Can operate High Performance Liquid Chromatography (Isocratic), UV-VIS spectrophotometer.
:
Area of Interest :
- Analytical Research and Development
- Quality Assurance
Additional Skills
1. Having the knowledge of basics of computer.
2. Efficient in delicate work of analytical practices with the least handling errors.
3. Able to work in team and individual as well.
Hobbies :
Listening music and Travelling.

[Guest]

CURRICULUM VITAE
SEERAPU SATISH
Email id : saatish83 AT gmail.com
Objective :
To achieve greater heights in career by sustained hard work, dedication and commitment to the organizational goals.
Job Summary :
1. Four years of experience in Bioanalysis.
2. Expertise in handling Analytical Instrumentation like HPLC and LC-MS/MS.
3. Experience in quantitation of drugs and metabolites in biological fluids using various extraction techniques.
4. Aware of the recent trends in US-FDA, UK-MHRA Guidelines.
5. Contributed for about 50 BA/BE pilot and pivotal studies both at Orchid and Aurobindo.
EDUCATION
- M.Sc., Biotechnology from Acharya Nagarjuna University campus, Guntur, Andhra Pradesh, during 2004- 2006 with 76.95%.
- B.Sc., (Microbiology, Biochemistry & Chemistry) from Gurunanak College of Science, Ballarpur (Nagpur University) during 2001-2004 with 65.25%.
PROFESSIONAL EXPERIENCE
1. Organization : Aurobindo Pharma Ltd. Research Centre, Hyderabad
Position : Research Associate III (Bioanalytical, CPD)
Duration : August 2009 till date.
2. Organization : Orchid Healthcare, Chennai
Position : Executive (Bioanalytical)
Duration : January 2008 to August 2009.
3. Organization : Acharya Nagarjuna University, Guntur
Position : Faculty for M.Sc and M.Tech Biotechnology
Current Job Responsibilities at Aurobindo
- Development and validation of accurate and cost-effective bioanalytical methods for the analysis of biological samples using HPLC and LC/MS/MS for drugs and metabolites.
- Analysis of plasma and urine samples for bioavailability studies.
- Routine calibration of HPLC and other equipments in the laboratory as per SOPs. Aware of the procedures for calibration of LC/MS/MS (API 3000).
- Involved as a team member in preparation and implementation of SOPs on laboratory instrumentation.
- Involved as a team member in designing analytical methodologies followed to validate the analytical methods.
JOB SKILLS
- Experience in bioanalytical method development and validation using LC-MS/MS (Sciex API 3000, Waters Micromass Quattro Premier) and HPLC.
- Well versed with regulatory Guidelines on Bioanalytical method validation and regulatory requirements for sample analysis.
- Documentation and handling of analytical data generated during method development, method validation and BA/BE studies.
- Positive attitude and the ability to work well with others.
PROJECT EXPERIENCE
1. Worked for three months on the project entitled “Molecular understanding of sc DNA- Actinomycin D interactions” at J.S.S Medical college and CFTRI, Mysore under Dr. K.S Jagannatha Rao during May to July 2006. (Handled circular dichroism, fluroscence spectrophotometer and Tm spectrophotometer).
2. Worked for three months on the project entitled “Transformation of Chickpea to enhance abiotic stress tolerance” at Department of Environmental Biology, University of Delhi, Delhi under Dr. P. Pardha Saradhi during May to July 2005.
OTHER ACTIVITIES
1. Knowledge of Statistical software like SAS
2. Published article in Current trends in Biotechnology and Pharmacy, Vol. 2 (3) 433-441 (2008) entitled “Studies on Actionomycin D induced changes in supercoiled DNA integrity”
3. Published a scientific article in the spectrum column of Science Reporter in January 2007 titled “Protein gels stops bleeding in a unknown way”.