www.biologicale.com Biological E Ltd Hyderabad : Biologics Manufacturing Manager

[krishni84]

biologicale.com

Head - Vaccine & Biologics Manufacturing:
Ph.D. in Life Sciences. At least 15 years relevant experience and at least 5 years experience in leading manufacturing teams in FDA approved vaccines/biologics plant catering to US and/or EU markets. Preference would be given to experience in viral or bacterial vaccines. Additional experience in design and commissioning of FDA approved biologics plants as well as exposure to QA would be preferred.

Key Responsibilities:
Manage all the biologics manufacturing activities of the company, Design strategies and systems to bring cGMP to FDA level. Able to provide long term strategies and play Key roler in planning new infrastructure

About Us
Biological E Limited was established over 50 years ago. It is the first private sector biological products company in India and the first pharmaceuticals company in South India. BE is also the pioneer in -preventive medicine. Originally incorporated as Biological Products Private Limited in 1953, and launched by Dr. D.V.K. Raju, Biological E today, is a leader in Vaccinology in India and a significant player in the world vaccine market. We are further expanding and enhancing the facilities and product lines for vaccines through the establishment of a new plant and R&D centre in Andhra Pradesh.

Contact Us
Biological E. Limited
18/1&3, Azamabad,
Hyderabad - 500 020,
A.P., India.
Phone 91-40-30213999 , 91-40-27617831 / 27617835 / 27615134
Fax 91-40-27615309 / 27616715 / 27630307
Kindly e-mail your resume at :corp@biologicale.co.in
Website : http://www.biologicale.com

[Guest-IJT]

V.Kulasekaran
- : 91-9789543243
E-mail: kulasekaran25 AT gmail.com

CAREER OBJECTIVE

To seek a good position in an ever-growing industry, where my knowledge and skill can be potentially applied for the benefit of the concern, along with an opportunity for my personal growth.


EDUCATIONAL QUALIFICATION
Course Institution / Board Year of completion Percentage
SSLC Amalorpavam Higher Secondary School, Puducherry. June 2002 91.60%
HSC Amalorpavam Higher Secondary School, Puducherry. May 2004 79.83%
B.Pharm College Of Pharmacy, Mother Theresa Institute of Health Sciences, Pondicherry University Puducherry. March 2009 68.23%

INDUSTRIAL EXPOSURE
- One month training in Production of Parenteral and Non-Parenteral dosage forms, QC and R&D areas in Caplin Point laboratories pvt. Ltd., Suthukeny, Puducherry.

COMPUTER SKILLS

- Proficient in working operating systems like Win98, Win2000 and WinXP.

CURRICULAR ACHIEVEMENT


- Presented poster on “Bioenchancer Activity of Cow Urine” at Fifth National Conference on Siddha medicine for All Ages
- Helped as Co-author on “Opthalmic Drug Delivary System - Recent Advances” at 23rd IPGA National Conference 2007, Chennai.
- Helped as Co-author on “Recant Trends in Oral Drug Improvment” – at 23rd IPGA National Conference 2007, Chennai.
- Helped as Co-author on at 54th IPC National Conference 2007,Warnasi

CO-CURRICULAR ACTIVITIES

- Worked as a Memento Committee Head & CD Release Coordinator in TEXO PHARMA VIRTUS’06, National Conference Organized in our college by Students of College of Pharmacy.
- An active Student Co-Coordinator in RED RIBBON CLUB in my college.
- Actively participated in workshop on “Life Skills Educationfor Nurses”at MTIHS

- Actively participated in 23rd IPGA National Conference 2007, Chennai.

- Actively trained in State Level Workshop on AIDS control by PACS, Pondy.

SKILLS ACQUARIED

- Chromatography, Spectrophotometer (UV), Flame Photometer,


PERSONAL DETAILS

FATHER NAME : R.VENUGOPAL
DATE OF BIRTH : 25-10-1986
MARRIAGE STATUS : UNMARRIED
NATIONALITY : INDIAN

LANGUAGES KNOWN:

- Tamil (Read, write and speak)
- English (Read, write and speak)

PERSONAL TRAITS

- Sincere and Hard-working
- Good planning capability and compliant nature.
- Regular and punctual candidate.

EXPERIENCE

- Worked as Production chemist in MILTON LABPRTORY for a period of two months.

- Now working as PACKING INCHARGE in FRANCE VITA NATURA PVT.LTD at puducherry

DECLARATION

I hereby declare that the above information is true to the best of my knowledge and belief.

DATE :
PLACE : PUDUCHERRY
(V.KULASEKARAN)

[Guest]

RESUME
Jhansi.B
Email : jhanu.yadav AT gmail.com
OBJECTIVE :
Looking forward for an opportunity where I can gradually improve my skills and utilize them for the welfare of organization.
Educational Qualification :
COURSE BOARD SCHOOL/INSTITUON YEAR OF PASSING PERCENTAGE
MSC(micro Biology) OU SHARADA 2011 71
B.Sc (Biotechnology) OU Nizam college 2009 70
Intermediate (Bi.P.C) IPE Sri Chaithanya college 2006 93
X standard SSC AVM.E.M 2004 80
Technical skills :
- MS-Office
- Net Browsing
Strengths :
- Hard working
- Interested to learn new things
- Take pride in doing good work & achieving good results
- Learning skills.
Participations :
- Participated as a volunteer in ‘Cancer Awareness program’ held at Nizam College during the period 2008.
- Have done project work in Red Cross Blood bank during the period 2008-09.
- Participated as a volunteer in college xpressions and management events.
(Jhansi.B)

[Guest]

Curriculum Vitae – L.Vijaya Sai
E mail : vijayasail AT yahoo.co.in
Scholastic / Academic Details :
Degree
Year of passing
Institution
Subject
Ph. D.
submitted August-2011
Dept. of Applied Microbiology,
Sri Padmavathi Mahila University, Tirupathi
Microbiology
M. Sc
2005
Bharathidasan University,Trichy

Microbiology
B. Sc
2002
Sri Venkateswara University, Tirupathi
Microbiology,MLT,Chemistry
Where, #
Ph.D .Thesis title : “Molecular and Physiological characterization of Phytate solubilizing bacteria from the gut of Earthworm ”
Thesis Adviser : Prof. Dr. K.Vijaya Lakshmi
MS.C. Project, Thesis title : “Bio-control of stem rot in ground nut incited by Sclerotium rolfsii
and invitro compatibility of potential native antagonists with fungicides
Thesis Adviser : prof.Dr.N.P.Eswara Reddy
Work Experience :
Duration
Position
Institute/Organization
Aug.2006 - july. 2011
Research Fellow
Responsibilities :
- Carry out Contract Research projects
- Training the students in the Areas related to Production, Purification and Characterization of Biotehnological Compounds of Industrial Significance.
Criya Biolabs,
Tirupathi
Nov .2006 - Mar. 2010
Guest Faculty
Subjects
- Molecular biology,
- Industrial Microbiology,
- Medical Microbiology
Sri Padmavathi Mahila University

Research Project for M.Sc., Degree

TITLE : Bio-control of stem rot in ground nut incited by Sclerotium rolfsii and
Invitro compatibility of potential native antagonists with fungicides
Abstract :
Groundnut is an important oil seed crop of tropics and sub-tropical regions of the world. Among the fungal diseases, Stem rot of groundnut caused by Sclerotium rolfsii is potentially very destructive disease. A detailed study on isolation of pathogen, rhizosphere mycoflora, antagonism of rhizosphere against S.rolfsii and integrated management of the disease with biocontrol agent. Eight different mycoflora were Aspergillus flavus, Rhizopus sp, Pencillium, A. niger and Trichoderma isolates (TGI, TG2, TG3, TG4) isolated consistently from the rhizosphere of groundnut. Among them TG2 isolate was found to be significantly superior over others in inhibiting the mycelial growth of S.rolfsii to the extent of 67.83%.
ORGANIZATION : Acharya N.G.Ranga Agricultural University, Tirupati

DURATION : 3 months during 2005
Publications :
L.Vijaya sai, P.Anuradha, K.Vijayalakshmi, N.P.Eswara Reddy, (2010) Biocontrol of stem rot of Groundnut incited by Sclerotium rolfsii and invitro compatability of potential native antagonists and fungicides. for the accepted paper for publication in “Journal of Pure and Applied Microbiology” vol(4).
L.Vijaya sai, Prof.K.Vijaylakshmi, N.D. Prasanna , S.K. Shaheen (2011) phytase producing Bacillus subtilis MTCC NO.9878 from the gut of Eisenia foetida The bioscan .IN PRESS will appear in 2011 dec.
L.Vijaya sai, Prof.K.Vijaylakshmi, N.D. Prasanna , S.K. Shaheen, K.Pavana Jyostna(2010) characterization and biochemical properties of phytase producing Bacillus subtilis . journal of BioScan vol (1)
S.Aruna, K.Vijayalakshmi, M.Shashikanth, K.Jyothi, M.Surekha, N.D. Prasanna, S.K.Shaheen and L.Vijaya sai (2009)First Report of Antimicrobial Spectra of Streptomyces tritolerans (Strain AS1) isolated from Earthworm gut (Eisenia foetida) Againist pathogenic and plant pathogenic Bacteria. Asian Journal Microbial Biotechnology Environmental science vol.(3)
S.Aruna, K.Vijaya Lakshmi, M.Shasikanth, K.Jyothi, M.Surekha Rani, N.D.Prasanna, K.Pavana Jyotsna, S.K.Shaheen, and L.Vijaya sai (2009).Optimization of Antibiotic compound produced by Streptomyces tritolerans (strain AS1) Isolated from Earthworm gut (Eisenia foetida) Asian Journal of Microbial Biotechnology Environmental Sciences Vol.(1)
N.D. Prasanna, Prof.K.Vijaylakshmi, L.Vijaya sai S.HarithaDevi,* P.Devika, S.K. Shaheen, K.Pavana Jyostna, (2009) Antimicrobial activity of Pseudomonas stutzeri isolated from earthworm gut(Eisenia Foetida) accepted Asian Journal of Microbial Biotechnology Environmental Sciences
S.K. Shaheen, Prof.K. Vijayalakshmi, N.D. Prasanna, K.Pavana Jyotsna and L.Vijaya Sai (2010). Enumeration and detection of nitrifying bacteria from the gut of earthworm (Eisenia foetida) Asian Jr. of Microbiol. Biotech. Env. Sc. Vol.(12), No.(4) : 913-916.
Research Findings presented in Symposia / Conference / Workshops :-
- Participated and presented a poster on “phytase producing Bacillus subtilis MTCC NO.9878 from the gut of Eisenia foetida” in International Conference held at Yogi Vemana University, Dept of Microbiology, 5-6th FEB 2009.
- Participated in National work shop on “Influence of microbes on the earth’s environment and inhabitants” at Dept of Applied Microbiology, SPMVV, Tirupati, 23-24th July 2008.
- Participated in National work shop on “Essentials of Gene cloning” at Dept of Applied Microbiology, SPMVV, Tirupati, March 3-5th, 2007.
- Participated in the National conference “Updates in Microbial Environment” at Dept of Applied Microbiology, SPMVV, Tirupati, in March 28-30th, 2008.
- Participated in National Conference on “Microbial Milestones” Department of Microbiology, Osmania University, January 24th-25th
- Participated and presented a poster on “Biocontrol of stem rot of Groundnut incited by Sclerotium rolfsii” in National symposium on “Emerging Trends in Microbiology Acharya Nagarjuna University Acharya Nagarjuna University Mar 25th -26th 2006.
- Participated in National Conference on “The role of Biotechnology in rural and industrial development” CRIYA Bio-labs Tirupati, 4th-5th July 2008
- National workshop on “Influence of Microbes on Earth’s Environment and its Inhabitants” APCOST & UGC Dept. of Applied Microbiology, SPMVV, TPT June 23rd-24th 2008
- National Workshop on “Emerging Trends in Biotechnology” UGC Department of Biotechnology, SPMVV, TPT, 29th march 2008
Research summary :
Abstract
Phytase is an important industrial enzyme hydrolyzing phytate to release inorganic phosphate. A microorganism with thermostable Phytase activity was screened from a total of 17 isolates from the gut of Eisenia foetida were collected from top ploughed horizon (0-20 cm) of vermicompost pit from and around Tirupati region, phytase producing microorganisms were selected by size of clear zone on the plate of Modified phytase screening medium (MPSM) and their phytase activities were measured by Trypti soya liquid assay method. An isolate PSB-1 was finally selected among some bacteria with a high phytase activity by determining thermo stability of phytase. The isolate was identified as Bacillus Subtilis MTCC 9878 by morphological observation, biochemical test, and 16s rRNA similarity analysis. The optimum activity of crude phytase Bacillus Subtilis PSB-1 was observed at 700c and pH 7.0 .The residual activity of the phytase was over 78% after heat pretreatment at 800c for 10 min, which indicates that this enzyme was to be highly thermostable .The crude phytase was also stable at broad range from 3.5-9.5 PSB-1 was the most efficient strain depending on its capability to solubilize P, utilizing a wide range of carbon, nitrogen sources and at different pH, temperatures.
Phytase production is carried out in phytase screening media supplemented with 2mM phytate per liter the culture broth was clarified by centrifugation, proteins were precipitated by adding 3 volumes of cold ethanol(-200c) and precipitate was redissolved in 100mM Tris –Hcl (pH7.5)supplemented with 1mM cacl2 and assayed for phytase activity as described by shimizu. One unit of phytase was defined as the amount of enzyme required to liberate 1 micromole of inorganic phosphate per minute.
And the enzyme is purified by 45%, 65% and 85% of ammonium sulphate fractionation and passing through PD-10 gel filtration column (Pharmacia)in to a 100Mm Tris-HCL buffer pH-7.5 and the molecular weight was determined by SDS-PAGE i.e.,46 kDa .
Earthworm is a unique habitat of its kind, was investigated as a source of bacteria to screen for the production of novel enzymes. Soil experiments were conducted by treatments as follows : (i)Untreated control, (ii) sodium phytate (sp) - 30 Kg P ha-1., (iii) Farm yard manure (FYM) – 40 Kg P ha-1, (iv) (FYM) – 40 Kg P ha-1 + (SP) - 30 Kg P ha-1. Plant growth promotion influenced by inoculation with phytate solubilizer was measured in terms of ground nut plant height and fresh weight and root length over uninoculated control after 15 days of germination results in the present study showed the efficiency of this isolate to make available P from sodium phytate in presence of farm yard manure. Plant growth promotion of ground nut was not increased significantly compared to controls.
Phytate solubilization is a complex process involving both organism and soil, needs more attention between laboratory methods to soil tests and seed inoculation experiments. Microbial phytases can be exploited for efficient conversions of phytate to phosphates when given as green manure to the soil for improved yield.
The present study concludes the gut flora of earthworms contribute phosphates to crops when supplemented to soil to replace the chemical fertilizer Phytase producing bacteria are substrate specific. They show greater resistant to proteolysis and better catalytic efficiency. Phytase has broad applications in biotechnology, therapeutics, agriculture and in reducing environmental pollution.

[Guest]

RESUME
Ms. G.Sunitha
E-mail : g.sunitha87 AT gmail.com
OBJECTIVE :
A career with a progressive organization that will use my education, skills, abilities and experience in an executive capacity, where I can effectively contribute to operations in any capacity that best matches my skills and experience.
EDUCATION :
- University college of technology
Osmania University
Post graduation : M.Tech(biotechnology),2009 (1st year : 81.5%)
Waiting for results

- T.K.R Engineering College
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY
Graduation : B.TECH( biotechnology), 2004-2008
Secured 76% marks
- St.Francis college for women
Intermediate board AP
Pre degree : BPC, 2002-2004
Secured 75% marks
- St.Rosy High School
SSC : 2002.
Secured 86% marks
EXPERIENCE :
- Worked as lab instructor from “Clonegen biotechnology Pvt ltd” From april-2008 to june-2008
- Worked as a teacher for higher standards in a school for 8months.
PRINCIPLE :
Desire to work, aspire to grow.
STRENGTHS AND ABILITIES :
- Positive mindedness and target oriented mindset makes me more focused
- Excellent communication skills
- Quick Learner (Learning from self and others mistakes)
- Will be ready to take any challenge.
IT SKILLS :
- Basic computer knowledge with MS Office,“C”, “C++“, SQL Server etc
AREAS OF INTEREST :
1) Molecular Biology
2) Genetic engineering
3) Immunology
ACHIEVEMENTS :
- Participated in “PRATHIBA” a state level technical meet and presented a paper on “GENETIC MODIFICATIONS”.
- Qualified PTPG-2009 conducted by JNTU
- Qualified PGCET-2009 and I-CET-2008
CONFERENCES AND WORKSHOPS ATTENDED :
- Participated in a National level workshop on ‘Recent Advances in Biotechnology’ held at T.K.R Engineering College, Hyderabad, A.P during 21-22nd February, 2007
B.TECH PROJECT :
Project Title :
”Biotechnological interventions for enhancing `Andrographolide' content of
Andrographis Paniculata” under the guidance of Dr.Archana Giri.
Description :
Andrographolide is a major constituent of Andrographis Paniculata is known for its high pharmacological importance. Its production is increased by using various tissue culture techniques which include
1. Elicitation
2. Colchicine treatment
3. Micro propagation
Increase in the Andrographolide is estimated by HPLC analysis
.
Place : Jawaharlal Nehru technological university
Duration : 4 months (nov-2007 to mar-2008)
2) PROJECT :
Project Title :
Isolation, production and characterization of “beta-galactosidase” from lactobacillus plantarum .under the guidance of Mr.R.P.Mishra.
Place : clonegen biotechnology pvt ltd.
Duration : 3 months (july 2007 to sep 2007)
TECHNIQUES KNOWN :
- Isolation of DNA
- Polymerase Chain Reaction (PCR)
- Electrophoresis : a) Agarose Gel Electrophoresis (AGE)
b) SDS-PAGE

- Chromatography Techniques : a) Paper Chromatography
b) Thin Layer Chromatography (TLC)
c) Column chromatography
- Colorimetry and Spectrophotometry
- Enzyme isolation, Immobilization of Enzymes (Entrapment Method)
- Immunological techniques : a) Immunodiffusion(RIA,Rocket ID)
b) Immunofluoroscence
c) Blood typing
d) Purification of RBC’s and WBC’s
- Microscopy, isolation of microbes, Pure Culture Techniques, Staining Techniques.
- Tissue culture techniques
EXTRACURRICULAR ACTIVITIES:
- Been N.C.C cadet and got ‘B’ certificate during 2002-2004.
- Participated in national level N.C.C camp held at Mehdipatnam
- Taken duties as Team Captain for the Shuttle Badminton team and represented in Inter-college competitions and got second place.
- Will be teaching poor and uncared children, whenever time permits