Natural Product Researcher Mumbai : Piramal Life Sciences

[krishni84]

Natural Products Chemistry

Position : Research Associate

Location : Mumbai

Reporting to : Group Leader

Education : M.Sc/M.Pharm/Ph.D (Natural Products Chemistry preferred)

Experience : 0-3 years

Desired Skills
· The candidate should be well versed in spectroscopy and structure elucidation of isolated bioactive molecules
· Chemical modification of natural products to address the pharmacological issues

Job Description-Bioactivity guided isolation of active molecules from microbes (Fungus, Actinomycetes from terrestrial and marine sources) and plants. The selected candidate would be performing extraction, different chromatographic techniques, TLC, HPTLC and handling the analytical /prep HPLCs. The candidate should be well versed in spectroscopy and in structure elucidation of isolated bioactive molecules. Chemical modification of natural products to address the pharmacological issues will form part of the job. The therapeutic areas would be antiinfective, anticancer, antiinflammation and antidiabetic.

Contact Us
Piramal Life Sciences Limited,
1, Nirlon Complex,
Goregaon (East),
Mumbai - 400 063.
Board No: +91 22 3081 8000
Fax No: +91 22 3081 8036
Mail your CVs to research.recruitment@piramal.com
Website : http://www.piramallifesciences.com

[Guest-IJT]

CURRICULAM VITAE

Keshav Ram Deshmukh
S/o Shri R. B. Deshmukh
Behind Sharma Saw Mill
Pachpedi Naka Raipur (C.G.)

Mob. : - 09926632191, 09826867931

E – Mail: keshdesh AT yahoo.com

Objective:
Professional research oriented opportunity with an organization where my commitment, skills and team-orientation will be of value and gives me a chance to update my knowledge and enhance my skills.

TITLE OF THESIS :"Formulation & Characterization of Mouth Dissolving Tablets of an Analgesic Anti-inflammatory Drug"Under the guidance of Dr. Sunil K Jain Lecturer SLT Inst. Of PharmaceuticalSciencesGuruGhasidasUniversity Bilaspur (C.G.).
PLACE OF RESEARCH PROJECT
ØSLT Inst. Of Pharmaceutical Sciences GGU Bilaspur (C. G.) India.

TRAINING EXPERIENCE
Ø45 Days training period from Zydus Cadila Ahmedabad.

Instrument Handled:
vDouble beam UV- Visible Spectroscopy.
vDissolution Apparatus (USP Type I & II).
vColorimeter.
vSonicater.

Extra Curricular Activities:
·Qualified in GATE -2007, all India rank- 3954.
·Participated as a Delegate and Task Committee member, in The APTI-13TH Annual National Convention-2008, held at SLT Institute of Pharmaceutical Sciences, GuruGhasidasUniversity, Bilaspur, Chhattisgarh during October 3-4, 2008.
·Presented a poster in the APTI 13TH Annual National Convention-2008, held at SLT Institute of Pharmaceutical Sciences, GuruGhasidasUniversity, Bilaspur, Chhattisgarh during October 3-4, 2008.
·Presented a poster in the National Seminar on “Advances in Drug Discovery and Development” organized by SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur [C.G.] on January 18-19, 2008.
·Participated in One Day National Workshop on “Vision 21st Century: Pharmacy Education and Career” organized by Institute of Pharmacy, Raipur Institute of Technology, Raipur held ON 3RD March 2008.

PERSONAL DETAILS
Name Keshav Ram Deshmukh
Date of Birth 04th May 1984
Father's Name Shri Ram Bishal Deshmukh
Permanent Address c/o Mr. Bheesham Deshmukh Behind Sharma Saw
Pachpedi Naka Raipur (C.G.) Pin- 492001.
Phone 09926632191, 09826867931.
E-mail ID keshdesh AT yahoo.com
Marital Status Unmarried.
Languages Known Hindi, English.

Hobbies Reading scientific books and journal.
Interested Area F&D, DRA, QA, Validation, Product Development.
REFERENCES

Dr. J.S. Dangi Mr. Ghanshyam Deshmukh
Professor in pharmaceutics Sr. Production Officer
SLT Inst. Of Pharma. Sci. Ranbaxy Labs. Pvt. Ltd. GuruGhasidasUniversity Bilaspur (C.G.). Dewas (M.P.)
Mob. No. 09827150112 Mob. No. 09826867931

DECLARATION
I hereby declared that the above in formations are true to the best of my knowledge and belief.

Date: 17-12-09 Yours Sincerely
Place: RAIPUR Keshav Ram Deshmukh

[Guest]

CURRICULUM VITAE
__________________________________________________________________
PANKAJ B. NARIYA
M.Sc.- Organic Chemistry
Ph.D- Phytochemistry (Natural Product Chemistry)
E-mail : pankajnariya AT yahoo.co.in
_________________ _________________________________________________
JOB OBJCETIVE
I am energetic, professional and self motivated doctorate person in chemistry with experience in Research and development and analytical laboratory. I have ability to work effectively and comfortably in a multi-disciplinary team under defined timelines and currently looking for a specific opportunity to achieve goal in respected pharmaceutical organization that allows me to be an integral part of the organization’s growth.
QUALIFICATION
- Ph.D. work in Phytochemistry, thesis on “Phytochemicals investigations, isolation, Characterization and Method validation of marker compound of some indigenous Cordia species” under guidance of Dr.V.J.Shukla, Head, Pharmaceutical Chemistry Laboratory, GAU, Jamnagar.
- M.Sc. in Organic Chemistry, from Saurashtra University, Rajkot with 66.81% (First class)
- B.Sc. (Chemistry) from D.K.V. Science College, Jamnagar with First class.
- Higher Secondary Education from Gujarat Secondary Education Board, Gandhinagar with Second class.
COMPUTER
- CCC exam pass from Institute of information & Technology (IICT) With Grade “A”
FIELD OF INTREST
- Research and Development in Organic (Synthetic R&D), Analytical Chemistry and Phytochemistry.

FIELD OF EXPERTISE
From the research experience, I have acquired following technical skills,
Delineation of pharmaceutical activity profile of natural products. Activity guided isolation of active principle in natural products.
Organic Mechanism and kinetic of organic reactions
Organic compounds and Drug Synthesis
Analytical Handling of Sophisticated instruments like HPLC, UV-Visible, IR and HPTLC, Polarimeter, Karl Fischer, Refractometer and Atomic absorption Spectrophotometer (AAS) for heavy metal analysis
Statistics Skills Handling Unscramble software for Analytical tool parametric and non-
Parametric statistic commonly used in biomedical Research. Application
of clustering and PCA, multivariate analysis to chromatographic and
Spectroscopic data analysis.
Spectroscopy UV- VIS, IR, NMR, Mass spectroscopy, Flame Photometry, Solvent extraction, electrophoresis technique, MWL Spectrum from TLC plates using scanner-3 (HPTLC).
Chromatography Expertise in column chromatography, paper chromatography thin Layer chromatography and chromatographic techniques, HPTLC, Planner chromatography (especially with respect to natural products), Optimizing multi-component mobile phase for natural product Extracts. HPLC gradient, isocratic elution pattern, method development and method validation
Computer Basic Windows-98, MS Office, Excel, Power point, PageMaker, Adobe Photoshop, Coral Draw, ACD system ware including ACD Labs ware, Win Cat etc.
RESEARCH EXPERIENCE (From Dec 2008 to till date)
- Drug discovery : Following bioactivity directed fractionation of Medicinal plants.
- Isolation and structural elucidation of natural compounds of promising biological
activity applying the conventional isolation and structure elucidation of Phenolic, Flavonoid, Alkaloid, Steroid and Terpenoids.
- Phytochemicals Screening of Natural Plant.
- Handling sophisticated Instrument like Atomic absorption (AAS) for Heavy metal analysis, HPLC, HPTLC, UV-Visible, HPTLC, and IR.
- Extraction of plant material by various solvent.
- Isolation, characterization, and Identification of marker compound by Chromatography and spectroscopic method.
- Qualitative & quantitative identification of complex organic mixtures, unsaturated alcohols, oxygenates olefins and aromatics etc. by chromatography and spectroscopy.
- Standardization of extraction fraction having active principle and its method validation.
DEPARTMENTAL WORK
- Physico-chemical parameters, Qualitative and Quantitative parameter of plants.
- Designing Solvent system for new compound.
- Handling HPTLC and HPLC on more than 100 samples of M.Pharm, M.D., and Ph.D Students of university.
Professional Industrial Experience
- Working in Analytical Laboratory as Quality control officer at Sparsh Bio tech. Jamnagar from June 2006 to Nov-2007.
- Working as an Analytical Chemist at Essar Petrochemical with Nalco Jamnagar from Nov-2007 to Dec-2008
JOB PROFILE
- Analysis of Raw and finished material, blends, bulks, antibiotics etc. by HPLC.
- Calibration and operation of instruments.
- Preparation and standardization of solutions and reagents.
- Developing method of new drug API on HPLC.
- Check Dissolution rate.
- IPQC (In Process Quality Control)
- Study of assay, force degradation, solubility of related substances
- Documentary work and reporting.
- Analyses of water samples of different streams.
- Monitored on-line instruments for DO, silica, pH and Conductivity etc.
AUDIT FACED Documentation & preparatory work for National and International Audits (Regulatory Agencies) FDA of Uganda, Blucross-india, WHO-G.M.P.
PUBLICATIONS
Acceptance of poster paper from 14th ISCB International Conference CDRI, Lucknow, India during January 15 – 18, 2010
Pankaj Nariya and V.J.Shukla. Evaluation of free Radical Scavenging Activity of Cordia Macleodii Bark (HOOK.F. & THOMSON).
P.N.Koringa, P.B.Nariya, N.R.Bhalodiya, V.J.Shukla. Chromatographic Standardization of Gokshuradi Guggulu by HPTLC Method. In pharma publication PCTE journal (Communicated)
Pankaj B. Nariya, Nayan R. Bhalodia, V.J.Shukla. In Vitro Evaluation of Antimicrobial and antifungal Activity of Cordia macleodii Bark. (HOOK.F. & THOMSON). Int J Pharma Tech Res.
Pankaj B. Nariya, Nayan R. Bhalodia, V.J.Shukla. Characterization of Fatty Acid Methyl Ester Contents of Cordia Macleodii (HOOK.F.& THOMSON) bark by Gas chromatography – mass spectrometry. Int J Pharma Res Dev.
Mukesh B. Nariya, Vinay J. Shukla, Pankaj Nariya, B.Ravishankar, Sunita Jain Ameliorative effects of Triphla on mucosal damage in rat model of Ulcerative colitis. Phytother Res (Under revision)
Pankaj B. Nariya, Nayan R. Bhalodia, V.J.Shukla Evaluation of Antimicrobial and antifungal Activity of Cordia Dichotoma Bark against multi drug resistant pathogens. Pubmed-Ayu (Under rivision)
PARTICIPATIONSIN SEMINAR/WORKSHOPS

- Seminar on stereochemistry at Saurashtra University, Rajkot-Oct, 2005
- Seminar on Nanotechnology at Saurashtra University, Rajkot-Oct, 2006
- Seminar on Role of regular affairs in pharmaceuticals industry Dr.Niranjan Singh.
Saurashtra University, Rajkot-Oct, 2006
- Seminar on Chromatography by Dr. R.T.ane.
- E- Resources workshop at Rajkot

[Guest]

SWIDLE PETER PEREIRA
Email id : swidleper AT rediffmail.com
swidleper AT yahoo.com
________________________________________
Educational Qualification :-
Name of the
examination Name of the
Board/ University Marks obtained
(percentage) Month andYear of passing Name of college from
Which appeared
T.Y.Bsc Mumbai University 70.13 % April -2009 Wilson College , Chowpatty
H.S.C Pune Board 73.33 % Feb -2006 Thomas Baptista , Papdy
S.S.C Pune Board 71.06 % March -2004 St. Anthony’s Convent High School.
- Recently finished with Final year of Masters course in Biotechnology from St.Xavier’s college, Mahapalika road, Marine lines with 1st class as per given by Mumbai university website.
Extra Curricular Activities :-
INTRA - COLLEGIATE COMPETITION
College Name Event Name Competition Month and Year
Wilson College MYCREW Poster Competition December 2006
Wilson College BIOMOSAIC Whizcraft November 2007
INTER – COLLEGIATE COMPETITION
College Name Event Name Competition Year
SVKM Mithibai college BIOTECHNOVA Quiz 2008
SVKM Mithibai college BIOTECHNOVA AD-Mad 2008
KC College BIOGENEI Biojewellery 2009

Area of Intrest :-
- My area of intrest includes Microbiology, Immunology, Molecular Biology , Virology , Biochemistry, Plant tissue culture and Animal tissue culture.
Work Experience :-
- Short term training programme in HPLC at Shri C.B.Patel Research Centre in May 2007.
- Completed a short term research project on “Determination Of Polyphenolic Content And Antioxidant Activity In Essential Oil Of Belonging To Family labiateae An Indigenous Herb” in May 2010.
- Had an Hands on experience with Animal tissue culture research project.
- Had an Hands on experience with Plant tissue culture.
Hobbies :-
- Sketching .
- Llistening to music.