CRAMS Scientist Chandigarh : Parabolic Drugs

[krishni84]

DEPARTMENT: Research & Development

LOCATION: Barwala/Derabassi

CRAMS:
Manager/Sr. Scientist/Scientists – (CRAMS & API): Ph. D./M.Sc. Organic Chemistry with 4 to 12 years of experience. Should have good communication & leadership skills and well versed with the latest development in area of synthetic chemistry and analytical instrumentation. Should have experience of developing small projects in lab and their scale up to pilot plant scale. Should be able to coordinate with peers in analytical, IPR, regulatory and production departments. Knowledge on IPR issues is also desired.

Research Associates/Chemists- (CRAMS &API):M.Sc. Organic Chemistry with 2 to 6 years of experience. The role demands an exposure to literature search, independently conducting the multi-step synthesis of small molecules and their characterization through the latest analytical techniques (UV, NMR, Mass Spectrometry, LC/MS).

The salary for all the above mentioned positions would be attractive and depends upon the experience and background of the candidates.

To apply for the above positions please e-mail your CV to hrd@parabolicdrugs.com with the job code.

About Us
Parabolic Drugs Limited is a vertically integrated, research based, Pharmaceutical manufacturer and exporter, specializing in development and manufacturing of Active Pharmaceutical Ingredients (API) and API intermediates. The Company has dedicated facilities for Custom Research and API manufacturing at its 4 locations, 2 in Haryana (India) and 2 in Punjab (India) and exporting to 45 countries across the globe from its WHO-GMP facilities. Parabolic has a wide Product basket, ranging from Oral and Sterile Semi Synthetic Penicillin API, Oral and Sterile Cephalosporin API in antibiotic segment to non-antibiotic API in the Cardiovascular, NSAID, Anti-Hypertensive and Osteoporosis segments.

Contact Us:
PARABOLIC DRUGS LIMITED
SCO 99-100, Level III & IV, Sector 17-B, Chandigarh - 160017, India
Telephone: +91 172 3914646
Facsimile : +91 172 3914645
E-mail : hrd@parabolicdrugs.com
Website : http://parabolicdrugs.co.in

[Guest]

CURRICULAM VITAE
U. Hanumantha Rao

E-Mail : hanumanth_rao76 AT yahoo.com
Career Objective :
A synthetic organic chemist with the expertise in the development of innovative processes & novel routes of Active Pharmaceutical Ingredients (API) and Intermediates through non-infringing, patentable and cost-effective process, scale-up for commercial production and assisting in documentation for filing in various regulated markets (especially Europe & US).
Summary :
I have 14 years experience in development, scale-up & technology-transfer for commercial production of API in various pharmaceutical industries as per GMP. I have handled more than 30 APIs. I have reduced cost of 8 API’s by 30-40% on scale-up. I have increased the Yield of 6-7API’s by 20-30%. I have a sound knowledge of trouble shooting during scale-up and technology transfer.
Expertise : An organic chemist by training with an expertise in the
- Development of non-infringing & patentable process for generic Active
Pharmaceutical Ingredients (API)/ Intermediates
- Scale up of the developed pilot plant
- Transfer of technology for the commercial manufacture of API/Intermediates for
advanced/regulated markets especially Europe & USA and Domestic market.
- Having good knowledge of reactors, centrifuges and production equipments.
Job profile :
Result-oriented professional with in-depth knowledge and functional experience of over 14 years in Team Leader in Research and Development lab. My job profile involves following activities :
- Designing synthetic patent non-infringing & patentable pathways for target
Structure after searching literature
- Exploring above pathways in the laboratory, pilot plant & plant level for various
Regulated markets
- Selection of the best approach/scheme producing API of acceptable specifications at
The minimum cost, measured at the manufacturing site
- Development, optimization and validation of selected scheme at the laboratory
level.
- Scale-up of Active Pharmaceuticals Ingredients from Laboratory level to pilot plant
level and trouble shooting at the pilot plant
- Validation of the selected approach at the pilot plant
- Transfer of the technology to the manufacturing site for commercial production
- Assistance and trouble shooting during product life cycle and ensure proper
documentation in filing DMF
- Setting specifications (in house) for raw materials, intermediates, solvents, drug
substance in collaboration with Scientist and Analytical Development.
Achievements & Credentials :
1. Reduced the cost of 7-8 APIs by just slight modifications in the process.
2. Improved the yield and quality of 5APIs on the pilot-plant.
Education
Master of Science (Organic Chemistry) from J.N.R.V University.
Bachelor of Science (Chemistry) from Andhra University.
Professional Experience
Since Jan 10
Team Leader in R&D Lab with Sri Venkateswara Medichem Lab Private Limited, Bollaram, Hyderabad
Dec'07 – Dec’09
Team Leader in R&D Department with Marksan's Pharma Limited, Pune in Kurkumbh, Maharashtra
Jul'06-Oct'07
Team Leader with Alembic Research Center (the Generic Lab), Alembic Limited, Gujarat, India
Jun'00-Jun'06
Executive with Aurobindo Pharma Unit-1(R&D Lab), Borapatla, Hyderabad, A.P.
Mar'99-May'00
Senior R&D Chemist in API with Taurus Chemicals Private Limited, Bollaram, Hyderabad, A.P,
May'95-Mar'99
R&D Chemist in R&D Lab with Sri Venkateswara Medichem Lab Private Limited, Bollaram, Hyderabad
Career Highlights
Successfully established Bupropion HCl, Gabapentin, Losartan Potassium, Metoprolol Tartrate, Resperidone, Rabeprazole Sodium and Lisinopril Di hydrate, Fenofibrate from R & D to plant.
Discovered new purification methods for different active pharmaceuticals ingredients in their different stages.
Conducted multitude of modifications in synthetic routs in various stages of the process, which resulted excellent improvement in yields and quality of the product.
Computer Skills
Well versed with MS Office & Internet Applications, Sythalline database.
Products Handled With :
Antipsychotics : Resperidone, Zolpidem.
Cardiovascular Drugs : Pentoxifylline (Vasodilator).
Anti Hypertensive : Losartan Potassium, Valsartan, Lisinopril Di Hydrate,
Ramipril.
Antiviral : Lamivudine, Capcetabine, Indinavir, etc.
Antifungal : Terbinafine Hydrochloride.
Anti Cholesterol : Atorvastatin Calcium, Simvastatin.
Antisecretory
(Antinuclear) : Rebeprazole Sodium, Pentoprazole Sodium.
Antidepressants : EsCitalopram, Bupropion.
Antibiotic : Azythromycin, Clarithromycin, Roxithromycin.
Other Products :
CefepimeHCl, CefiximeTrihydrate, Cefaclor, Cefprozil.
Cephalosporins.

[Guest]

Prafull Kumar Saurabh


Prafull.saurabh AT gmail.com




Career Objective
A growth oriented and challenging position in a progressive organization where my skills are utilized in the best way with a scope of learning, innovation and career development




Professional Qualification

M.Sc from Grukul Kangri University Haridwar in Analytical Chemistry,

Area of Specialization : Commercial method of chemical analysis.

TRAINING : Three month industrial training in DABUR PHARMA LIMITED BADDI (H.P).

Job Profile –
1. Having about 2.8 years experience in Ranbaxy laboratories limited.
2. Having 1.5 years experience in Indswift laboratories limited.

RANBAXY LABORATORIES LIMITED :
In Rannaxy Labs Ltd. worked in stability department as a Officer from 9th July2007 to 20th march 2010.

INDSWIFT LABORATORIES LIMITED :
Presently working in Analytical department as a Research officer from 5th April 2010 to till date

Job Responsibilities :
Ranbaxy Exeprience :-(Stability Department)
- Analysis of Stability studies of Finished Products
- All document works concerned to Stability.
- Study of Stability.
- Preparation of COA’s , Girds and Data review.
- Working as per USFDA,WHO & cGMP requirement.
- All types regulatory documentation in Stability deptt.
Job Responsibilities :
Indswift Exeprience :-(R & D-Analytical Department)
- Method development of Raw materials ,intermediates product and final product.
- Validation of final product.
- Calibration of instrument , HPLC ( waters), UPLC( waters), HPLC (dionex)
- Preparation of COA’s and analytical test report( ATR).
- Method transferred in QC LABS.
- Method development and validations of ionic compound( Cation and Anion) like as Sodiun, potassium,Tetrabutyl ammonium hydroxide , sulphite,nitrite, chloride and bromide in final API and intermediates by ion exchange chromatography.
Project handeled :
- Sunitinib L-maleate
- Deferarirox
- Rifaximin
- Verdenafil tri hydrate
- Eletriptan Hydrobromide
- Tapentadol

Instruments Handling :
- ION Chromatography (Dionex –ICS 5000)
- HPLC (Waters with empower software, Agilent- with empower softwar, Dionex- with Chromleon software)
- UPLC (Waters -with empower software)
- UPLC (Dionex -with Chromleon software)
- UV (Shimadzu UV)
- Karl Fischer Titrator (Metrohm)
- Dissolution Apparatus (Distek)
Personal Attributes
- Capability of taking responsibility.
- Good group activities & Smartness with Honesty.

Personal Information :

Date of Birth : 20th March 1986

Sex : Male

Nationality : Indian

Marital Status : Married


Languages Known :


English & Hindi


Computer Proficiency
I am Comfortable with the following application packages :

- Internet
- MS Word
- MS PowerPoint

Academic Record

B. Sc (in 2005)

Rohilkhand University, Bareilly
- With Major Subjects Math & Chemistry.

Intermediate (in 2002)

Uttar Pradesh Board, Allah bad
- Done in Science.
- Major subjects Included Physics, Chemistry, & Math.
Matriculation (in 2000)

Uttar Pradesh Board, Allah bad
o Done with Math, Science.