www.advinus.com Therapeutics Pvt Ltd Pune : Research Scientist

[Admin]

Research Scientist/Senior Research Investigator(Screening) - Discovery Biology (Code : ATPL/DB/PUN)
advinus.com

Job Description :
* Expertise in developing and optimizing various in vitro assays on different platforms and target types
* Expertise in cell culture
* Experience in protein expression & purification
* Experience in leading a small team of scientists
* Ability to handle multiple projects at the same time
* Good communication and interpersonal skills

Qualifications :
* M.Sc. in Biotechnology, Biochemistry or related field
* 5+ years of experience in the Pharma R&D sector

Other Info : Code: ATPL/DB/PUN - Location : PUNE

Apply here:
http://www.advinus.com/jobApply.asp

Advinus Therapeutics Pvt. Ltd.
Quantum Towers,
Plot No 9, Rajiv Gandhi Infotech Park,
Phase – I , Hinjewadi,
Pune – 411057, India
Tel : +91-20-66539600,
Fax : +91-20-66539620

Advinus Therapeutics Pvt. Ltd.
#21 & #22 Phase II, Peenya Industrial Area
Bangalore 560058, India
Tel : +91 80 2839 4959
Fax : +91 80 2839 4015

Advinus Therapeutics is a research-based Pharmaceutical Company founded by leading global pharmaceutical executives and promoted by the TATA Group. The company is the first of its kind in India to offer end-to-end development services to the global Pharma, Agro and Biotech industries and at the same time creating long-term value through internal and collaborative innovative Drug Discovery.

[Guest]

Wan't to apply in your company. I have done my M. Sc in Biochemistry from Department of Chemistry, University of Pune

[Guest]

RANI B. MENON
E-mail : ranibm21 AT yahoo.com
QUALIFICATION : Ph.D., Organic Chemistry
PROFESSIONAL EXPERIENCE
December 2005-June 2010
Chemistry Department, Astrazeneca India Pvt Ltd.
Designation : Research Scientist 1
June 2009- till date : Mtmk2: Fragment based library generation, devised methods for exclusive formation of sulfoxides and sulfones. Designed synthesis of various quinolin-2-ones, ~50 molecules were submitted including certain intermediates
Feb 2009-May 2009 : MQFF1 project: 10 molecules submitted (7-9 steps each).
April 2007-Feb 2009 : X1 project: ~ 45 molecules submitted along with scale-ups of intermediates and molecules (10-30g) (5-7 steps each).
Jan 2007-March 2007 : X2 project: Re-syntheses of 4 Vertex molecules using new routes (9-13 steps each).
Dec 2005-Dec 2006 : ALS projects: The project made a LO transition in 1Q 2006, since no efficacy could be achieved in animal model it was discontinued. Submitted 35-40 molecules and about the same number of intermediates.
March 2003- November 2005
Department of Medicinal Chemistry, University of Mississippi, USA
Designation : Research Associate
Job Description :
- To design and synthesise molecules to act as anti-infectives, mainly derived from natural products. Current studies directed towards anti- malarial and anti-Leishmanial drugs and/or pro-drugs based on SAR.
- Synthesis by way of parallel synthesis and conventional methods.
- Class of compounds : natural products like artemisinin and others.
Aug 1999-Feb 2003
Hygeia Laboratories, Pune, India
Designation : Head, Research
Job description :
- Research : Contract research and contract synthesis, and developmental research for viable processes mainly of pharmaceutical interest.
- Process research activities involving synthetic organic chemistry at the bench scale and scale-up activities in large glassware.
- Develop viable technologies/processes for fine chemicals including Chiral molecules, via multistep synthesis and/or resolution techniques, and bulk actives in a GMP like environment.
- Responsible for staff induction and training programs.
May 1998- July 1999
Dai-Ichi Karkaria Ltd., Pune, India.
Designation : Deputy General Manager (R & D Pharm.).
Job description :
- Set up the R & D facility and initiated the pharmaceutical research program, which involved modification of the existing facility for research work.
- Planning of the research program and procurement of instruments and chemicals through direct interaction with the vendors.
- Recruiting of personnel for the project by interviews.
- Planning and execution of research program on process development for manufacture of pharmaceutical products pertaining to maternal care.
- Class of Compounds : Prostaglandins
Dec 1996-April 1998
Astra Biochemicals Pvt. Ltd. ( Now Astrazeneca India), Bangalore, India.
Designation : Scientist. Division of Medicinal Chemistry.
Job description :
- Drug discovery-Design and synthesis of new molecules for anti tubercular activity.
- Develop lead compounds for drug molecules.
- Synthesis of molecules for anti-tubercular activity, to serve as single drug therapy with high efficacy, fast acting, short-term therapy (compared to the existing long-term multi-drug therapy) and with no effective recrudescence of the mycobacterium.
- Molecular design and modifications were based on the results of in-vitro and in-vivo assays, and pharmacokinetic studies
- Class of compounds : Heterocycles.
June 1992-Nov 1996
Astra Research Centre India, Bangalore, India.
Jan 1995-Nov 1996 : Scientist. Division of Medicinal Chemistry.
Job description :
- To coordinate the research activities with the medicinal chemists carrying out synthesis, molecular biologists and biochemists conducting the biological assays, the staff performing the animal model studies and with scientists at the computer aided drug design cell.
- Design and synthesis of new drug like molecules for anti-malarial activity against Plasmodium falciparum, which would be fast acting and should kill the parasite and clear the infection without recrudescence.
- Synthesise molecules of the kind that could be administered orally.
- Class of Compounds : Aromatic Heterocycles
Jan 1994-Dec1994 : Senior Post Doctorate Fellow. Division of Medicinal Chemistry.
Job description:
- Design and synthesis of new antimalarials.
- Class of Compounds: Aromatic Heterocycles
June1992-Dec1993: Junior Post Doctorate Fellow. Division of Medicinal Chemistry
Job description:
- To develop a viable synthetic route for the synthesis of prostaglandins. Synthesis of prostaglandin, namely carboprost methyl ester was carried out via the convergent three component coupling method and the two component coupling method.
RESEARCH EXPERIENCE
- Nov 1990-Dec1991
Post-Doctoral Associate, Department of Chemistry, Rutgers University, New Jersey, USA
Advisor: Professor Spencer Knapp
Subject: Synthesis of Porphyrin analogs to study its photophysics and learn about the electron transfer reactions between two metallated porphyrins in a dimeric special pair.
- Feb 1990-Oct 1990
Research Associate, National Chemical Laboratory, Pune, India.
Development of a commercially viable method for several biologically important prostaglandins.
- Feb 1985-Jan 1990
Ph.D., Research fellow of the Council of Scientific and Industrial Research, National Chemical Laboratory, Pune, India.
Advisor: Dr. T. Ravindranathan
- Developed a highly stereospecific synthesis of the biologically important - -lipoic acid and its analogs through stereospecific alkylation of chiral sulfoxides utilising recyclable chiral auxiliaries.
- Application of chiral sulfoxides in stereospecific alkylations, addition reactions and 1,2-carbonyl transpositions.
- Synthetic studies on the spiroketal construction for the ionophore antibiotic calcimycin involving Diels-Alder reaction to direct the four stereocenters of the seven chiral centers present in the molecule.
- Stereoselective synthesis of a potential antimalarial drug, artemisinin, via a highly stereospecific intramolecular Diels-Alder reaction starting from readily and abundantly available (+)-isolimonene.
PUBLICATIONS
- “Stereospecific Synthesis of - -Lipoic Acid”. Tetrahedron Letters, 1987, 28, 5313.
Rani B. Menon, M.Anil Kumar, T. Ravindranathan.
- “Structure of bornana-2-spiro-2’-(6’-methyl)-1,3-dithiane-1’-sulfoxide”. Acta Cryst., 1989, C45, 1088. N.N.Dhaneshwar, R.B.Menon, S.S.Tavale, T.N.Guru Row.
- “Stereoselective synthesis of Artemisinin”. Tetrahedron Letters, 1990, 31, 755 T.Ravindranathan,M.Anil Kumar, Rani B. Menon and S.V.Hiremath.
- Synthesis and biological evaluation of C-9 modified artemisinin as prodrugs against leishmaniasis and malaria. J. Med Chem, 2005 Rani B. Menon, K.M.Muraleedharan, Dr.Babu Tekwani, Dr Mitchell A. Avery (manuscript under preparation)
- New C-9 atremisinin derivatives to target leishmaniasis and malaria. Dr. Mitchell.A. Avery, K.M.Muraleedharan, R.B.Menon, Dr.Babu Tekwani (manuscript under preparation)
- Method of the preparation and anti-infective activities of new C-9 modified artemisinin analogs. Dr.Mitchell A. Avery, K.M.Muaraleedharan, R.B.Menon (US patent to be filed)
PRESENTATIONS
- Rani B. Menon, M.Anil Kumar, T.Ravindranathan,
“Stereospecific Synthesis of - -Lipoic acid”,
VIIIth Indo-Soviet Symposium on the Chemistry of Natural Products, December 8-12, 1986, Hyderabad, India.
- T.Ravindranathan, M.Anil Kumar, Rani B. Menon and S.V.Hiremath
“Stereoselective Synthesis of Artemisinin”, XVIIth IUPAC Symposium on Chemistry of Natural Products, February 4-9, 1990, New Delhi, India.
SKILLS:
- Communicate, coordinate and work well in an interdisciplinary team.
- Delegate and empower team members to work enthusiastically.
- Analytical techiniques: use and operations of NMR, FT-IR, LC-MS, UV spectrophotometers.
- Computers: Microsoft Office, Adobe Photoshop, Chem Draw.
ACADEMIC RECORD
- Ph.D. Organic Chemistry-1990
- National Chemical Laboratory, Pune, India
- Thesis Title: Synthetic Studies on Biologically Active Compounds
- Research Advisor: Dr.T.Ravindranathan
- M.Sc. Organic Chemistry-1984
- Department of Chemistry, University of Pune, Pune, India
- B.Sc. Chemistry (main), Biology (Subsidiary)-1982
- University of Pune, Pune, India.
Personal:
Date of birth:21/09/61
Languages spoken: English, Hindi, Marathi, Malayalam & Tamil
REFERENCES
Available upon Request

[Guest]

hello sir,
am divija have completed my b.e in biotech,wanted to know whether i can get any job in your company.
thanking you

[Guest]

Santanu Chakravorty, Ph. D
Post doctoral Research fellow
University of Witwatersrand E-mail : santanu_org AT yahoo.com
Johannesburg
South Africa (Nationality : Indian)
Objective
Highly motivated and experienced synthetic and material chemist with more than six years of research experience in the area of Synthetic Organic, Material and Bioorganic Chemistry.
Experience / Skills
- Expertise in writing publications
- Experience in multi-step synthesis of different target molecules
- Experience in software application : Chemdraw, ISIS draw, Reaxys, Excel, Adobe photoshop, etc. DFT
- Proficient in preparing project reports/ updates for internal and external presentations
- Experience in Operating Instruments : 300/400MHz NMR spectrometer, FT-IR spectrometer, POM, Differential Scanning Calorimeters (DSC)
Education and Appointments
4/2010 – Till the date Postdoctoral Research Fellow, Division of Organic Chemistry/medicinal chemistry, University of Witwatersrand, Johannesburg, South Africa
2010 Ph. D, Organic Chemistry, University of Kalyani, West Bengal, India
Thesis title : Synthesis and characterization of liquid crystalline materials Supervisor: Prof. K. C. Majumdar
2004 Master of Science (Organic Chemistry)
North Bengal University, West Bengal, India
2002 Bachelor of Science (Chemistry), North Bengal University, West Bengal, India
Honours/ Awards
- Postdoctoral Research Fellowship (NRF Innovation Fellowship), University of Witwatersrand, Johannesburg, South Africa, April 2010- Till the date
- Council of Scientific and Industrial Research(CSIR), Government of India, Ph. D Research Fellowship, February 2005- January 2010
- NET (National Eligibility Test, organized by CSIR, Government of India), 2004
- GATE (Graduate Aptitude Test in Engineering, organized by IIT, Government of India), 2004
Publications
Research articles
1. Majumdar*, K. C.; De, N.; Chakravorty, S. “Palladium-mediated bis-arylation of inactivated and activated arenes”. Synthetic Communication, 2011, 41, 121
2. Majumdar*, K. C.; Ghosh, T.; Chakravorty, S.Palladium-mediated reductive Mizoroki-Heck cyclization strategy for the regioselective formation of dibenzoazocinone framework. Tetrahedron Letter, 2010, 51, 3372
3. Majumdar*, K. C.; Sinha, B.; Ansari, I.; Chakravorty, S Molecular Iodine Mediated Intramolecular Cyclization : An Efficient Method for the Synthesis of Benzoxepine Derivatives. Synlett, 2010 , 1407
4. Majumdar*, K. C.; Chakravorty, S.; Ghosh, T. “Palladium-Mediated Reductive Heck Cyclization for the Formation of Dibenzoazepinone Framework.” Synlett, 2009, 3127.
5. Majumdar*, K. C.; Chattopadhyay, B.; Chakravorty, S. “An expedient palladium-mediated intramolecular cyclization route to the synthesis of bis-fused benzofuran and a two-directional ring closing metathesis for the synthesis of bis-benzoxepin and bis-benzooxocine”. Synthesis, 674, 2009.
6. Majumdar*, K. C.; Chattopadhyay, B.; Chakravorty, S. “Bis-fused benzofurans, bisbenzooxepines and bisbenzooxacines”. Synfacts, 2009, 5, 0499.
7. Majumdar*, K. C.; Chakravorty, S.; Ray, K. “Palladium-mediated direct synthesis of N-substituted 4-methyl and 4-ethylisoquinolone derivative”. Synthesis 2008, 2991.
8. Majumdar*, K. C.; Chakravorty, S.; De, N. “Palladium-mediated bis- and tris-biaryl Heck coupling for the synthesis of heterocycles”. Tetrahedron Lett. 2008, 49, 3419.
9. Majumdar*, K. C.; Chakravorty, S.; Shyam, P. K.; Taher, A. “Palladium-mediated Heckreaction to the synthesis of 3-substituted indoles and indolones framework”. Synthesis 2009, 403
10. Majumdar*, K. C.; Chakravorty, S.; Taher. A. “New efficient RCM-mediated synthesis of pyrrolidine derivatives.” Synth. Commun. 2008, 38, 3199.
11. Majumdar*, K. C.; Sinha, R. K.; Chakravorty, S. “Induction of B1Phase in binary mixture of rod-shaped and bent-shaped mesomorphic compounds.” Journal of Physics and Chemistry of Solids 2009, 70, 1171.
12. Majumdar*, K. C.; Chakravorty, S.; Pal, N.; R. K. Sinha “Synthesis and characterization of cholesterol-based nonsymmetric dimers terminated with ferrocenyl core.” Tetrahedron 2009, 65, 7998
13. Majumdar, K. C.; Chakravorty, S.; Sinha, R. K.; Pal. N. “Synthesis and characterization of bent-shaped material derived from benzophenone moiety”. Molecular crystal liquid Crystals 2009, 515, 123.
14. Majumdar*, K. C.; Chakravorty, S.; Pal N.; Nandiraju V. S. Rao “Synthesis and thermal behavior of chiral oligomers derived from cholesterol”. Tetrahedron 2009, 65, 152.
15. Majumdar*, K. C.; Chattopadhyay, B.; Chakravorty, S.; Pal, N.; Sinha, R. K. “A new type of symmetrical banana-shaped material based on N-methyldiphenylamine as a core moiety exhibiting an Ad- A¬2 transition”. Tetrahedron Lett. 2008, 49, 7149.
16. Majumdar*, K. C.; Chakravorty, S.; Pal, N. “Synthesis and characterization of five ring achiral banana-shaped material showing B2 phase”. Molecular crystal liquid Crystals 2009, 503,112.
17. Majumdar*, K. C.; Ghosh, T.; Chakravorty, S, Synthesis and characterization of Symmetrical eight aromatic ring containing bent-shaped material derived from benzophenone. Molecular Crystal Liquid Crystal, 2010, 533, 63.
18. Majumdar*, K. C.; Ponra, S.; Chakravorty, S, Synthesis and Charecterization of cholesterol-based tetramer Molecular Crystal Liquid Crystal, 2010, 528, 113
19. Majumdar*, K. C.; Shyam, P.; Chakravorty, S, Synthesis and characterization of unsymmetrical six-aromatic ring containing bent-shaped compounds Liquid Crystal, 2010, 37, 1237
20. Majumdar*, K. C.; Ghosh, T.; Chakravorty, S, Pal, N.; Rao, D. S. S.; Prasad, S. K. Cholesterol based unsymmetrical Schiff’s base dimer terminated with 4-alkoxy-5-phenylthiophene unit : Synthesis and characterization Liquid Crystal, 2010, 37, 1539.
References
Will be available upon request

Major Projects Developed
Project 1 : Quinone-piperazine-choleseterol based conjugate:
We have developed a method for the synthesis of quinine-piperzine-cholesterol based conjugate for anticancer activity. This project is still in the way some compounds still have to be synthesized.
Project 2 : Synthesis of novel biologically active compounds with covalently bound carbohydrates through a PEG-linker attached by way of an activated ester
We cross-linked carbohydrates with activated esters, through a PEG linker with different functionalities and varied chain lengths. Our goal will be to see the dependency of biological activity on the functionalities and on the variable length of the PEG-linkers
Project 4 : Synthesis of novel potentially biologically active compounds with covalently bound lipids and carbohydrate through a triazine linker
- Applying multistep process we have synthesized different alkyne sugar derivatives
- Applying multistep process we have synthesiszed cholesterol-azide derivaes
- We have a developed the Cu-based triazine linker between carbohydrate and lipids.
Project 5 : Synthesis of protein kinase inhibitors
We have prepared a series of moieties containing both anthranilic and piperazine and they tested for protein kinase inhibitors
Project 6 : Synthesis and characterization of liquid crystalline materials:
- Synthesis of cholesterol based materials (for example rod-shaped materials by multistep synthesis)
- Synthesis of bent shaped liquid crystalline materials (based on diaminobenzophenone, diamino-diphenyl amine, m-nitrophenol)
- Characterization of those materials with POM, DSC and HRXRD experiments.
Project 7 : Synthesis of Heterocyclic Compounds
- Pd-mediateded Songashira cross coupling followed by Pd-mediated reductive Heck coupling (synthesis of dibenzoazepinone and dibenzo azecinone framework)
- Pd-mediated intramolecular Heck Coupling (synthesis of N-substituted isoquinolone, bis benzofuran, cyclization of inactivated and activated arenes and bis-, tris- cyclisation)
- Oxy-Claisen rearrangement (synthesis of bis benzofuran)
- Ru-catalysed (Grubb’s catalyst) cyclization (synthesis of bisbenzofuran)
- Molecular Iodine mediated cyclization (synthesis of benzoxipene derivatives)

[Guest]

hello, i am a m.pharm graduate in pharmaceutical chemistry (analytical chemistry) with first class. Finding job related to same qualification in pharmaceutical company in pune. pls do the needful and hope for the reply

[Guest]

CURRICULUM VITAE
Name : Mr. BALSANE KISHOR EKNATH
E-Mail Address balsane_kishor86 AT rediffmail.com
kebalsane AT gmail.com
Seeking a position to utilize my skills and abilities in an organization that offers professional growth while being innovative and resourceful, so as to contribute my best for growth of organization.
M.Sc. (Organic chemistry), UNIVERSITY OF PUNE.
Exam Details Board / University Percentage Year of Passing Class
M.Sc.(Organic Chem.) University of Pune 63.1 % 2009 Ist
B.Sc.(Chem.) University of Pune 75.75 % 2007 Ist with Dist.
H.S.C. Maharashtra State 51% 2004 II nd
S.S.C. Maharashtra State 70.70% 2002 Ist with Dist.
3Dece 2009to31st may 2010 : Innovassynth Tech. Ltd(I), Khopoli.(CRO
in R &D Deptt.)
1june 2010to till date : Pfizer pharmaceutical(I) Ltd.mumbai.
(in chemical research & development department)
I was working on project :- 1) ARYL PYRAZOLE
2) PHENICOL INTERMEDIATE
3) RACTOPAMINE HYDROCHLORIDE
4) TRPV
4) DTCT-U 5) URIDINE AMIDITE
A Research Project :- SYNTHESIS AND CHARACTERIZATION
OF BIOLOGICALLY IMPORTANT PYRAZOLINES”
AT. S.S.G.M College Kopargaon
- Seeking assignments in R&D Department with Pharmaceutical Industry
Take active part in organizational growth and simultaneously grow professionally.
Like to handle challenging/difficult tasks due to confidence, hard work, positive attitude, team work which is helping me to grow faster.

- Column purification
- Crystalization technique
- Precipitation technique
- Solvent extraction
- Strengths
- Strengths
- AUTOMATIC LAB REACTOR (ALR)
- DE-DIETRICH 20 LITRES REACTOR
- KARL FISCHER
- AUTOCLAVE HYDROGENATOR(100ML,1LITRE,5LITRE)
- MANNUAL HPLC
-
- NMR
- Witting Reaction
- florination reaction
- Still coupling
I was handling reagent NaCNBH4, NaBH4,Hexafluro acetone,DMF_DMA,Socl2, thiocabonyl di imadazole,
Also chandelled DAST(florinating agent),pd(pph3)4,hexamethyliditin,

I was handling Grignard reagent isopropyl magnessiumchloride.
I was aware about hydrogenation reaction used reduing reagent pt/c & pd/c .

I was handling moisture sensitive reaction.
also aware about protection & deprotection reagent such asH-F pyridine,DMT-CI,phos reagent,

[Guest]

CURRICULUM VITAE
KRISHNA MURARI

Email : krishnabiotech51 AT gmail.com
CAREER OBJECTIVE
To be working in the biotechnology industry enhancing my knowledge and producing effective results.
ACADEMIC QUALIFICATION
Degree Univ./Board College/School Year of passing Result
SSC BSEB,PATNA HIGH SCHOOL
BAKHARIDOA,VAISHALI 2003 53%
HSC BIEC,PATNA DR.R.M.L.S.COLLEGE,
MUZAFFARPUR 2005 51%
B.Sc. Biotech.(Hons.) B.R.A.B.U
MUZAFFARPUR DR.J.M.COLLEGE
MUZAFFARPUR 2008 69%
M.Sc
Biotechnology.
MAGADH UNIVERSITY,BODHGAYA A.N.COLLEGE,PATNA 2009-11
(PRE)
FINAL 70%
( Pre.)
Final Yr.
( R A)
AREA OF INTEREST
Molecular biology, Biochemistry, Cell biology, Environmental Biotechnology
TECHNIQUES KNOWN
- Isolation & purification of nucleic acids
- Purification of protein
- Gel electrophoresis & SDS–PAGE
- Western blotting
- PCR & Real Time PCR
- BACTEC 460 TB System
- Genetic techniques (phage lysate preparation, transduction, transformation, conjugation, transpositional mutagenesis)
- Microbiological techniques (media preparation, inoculation, antibiotic sensitivity, Gram’s staining, AFB staining, light microscopy)
- Fast plaque assay
- ELISA
- Spectrophotometry
- Paper chromatography & TLC
- Histopathology (tissue fixation, processing, embedding, sectioning, preparation of fixatives)

SEMINARS/CONFERENCES ATTENDED
- National symposium on climate change and sustainable development in Magadh Mahila college, Patna University, patna.
- Participate in National Seminar On Importance Of Medicinal And Aromatic Plants In Bihar Economy organized by OSD state Medicinal Plants Board, Health Dept., Govt.of Bihar.
- Participate in impact of Environmental pollutants on Health and Fertility at Mahavir Cancer Institute and Research Centre Patna Bihar.
- Participate in Ntional Seminar On Applications Of Biotechnology & The development of Bihar, organized by Central university Of Bihar & Birla Institute Of Technology.
WORKSHOPS ATTENDED
- Amity Institute Of Microbial Sciences, Amity university, Lucknow, Topic – Application of Nanotechnology in Microbial & Herbal Product Development.
- National Institute of Pharmaceutical Education and Research (NIPER) Hajipur Rajendra Memorial Research Institute of Medical Sciences (RMRIS),Patna. Topic – Advance Separation Technology.
PROJECT EXPERIENCE
1. Tirhut Udyog Limited Sudha Dairy,Muzaffarpur.
- A project entitled “On Bacteriological Test”,
From 23/05/2006 to 22/06/2006.
2. Dr.J.M.College Muzaffarpur.
- A project entitled “Tissue Culture Studies Of Wild Species Of Solanum Nigrum Dr. L.N.Shukla, University Department Of Botany, B.R.Ambedkar Bihar University Muzaffarpur Bihar.
From 19/07/2008 to 13/09/2008.
3. Auroprobe laboratories, Ghaziabad. (Uttar Pradesh).
A project entitled “Comparative Study of PCR and BACTEC 460 System for the detection of pulmonary tuberculosis.
From 02/11/2010 to 01/03/2011.
Work Experience
Having one year work experience as a Lab Technician in Auroprobe laboratories,Ghaziabad. Uttar Pradesh.

[gyan_ishwar]

RESUME

Mr. Dnyaneshwar Bhanage.

Email : dnyaneshwar.bhanage1985 AT gmail.com
gyan_ishwar AT rediffmail.com

CAREER GOAL CAREER GOAL
CAREER GOAL :
- To pursue a rewarding career in the field of synthetic and medicinal chemistry research.
- Ambitious to work interface between synthetic organic chemistry and biology.
PRESENT ORGANISATION :
- Currently working as research chemist in “TCG Life Sciences” Pune division
From March 24 till date in R&D Department.
EXPERIENCE AND SKILLS :
- From July 2008 to March 2010, I worked as a R&D Officer in “Unimark Remedies Ltd” Pune division in oncology API R&D Department.
Here I have worked on anticancer projects (from literature survey, R&D, optimization, Lab scale up validation) like
Irinotecan hydrochloride trihydrates, Gemcitabine hydrochloride, 7-ethyl-10- hydroxy camptothecin and Topotecan hydrochloride.
- Since March 2010 to till date I am working as a Research chemist in TCG Life Sciences, Chembiotek Research International Pune (India). Here I have worked on projects of different leading pharmaceutical companies like Bayer Crop Science, International AIDS & VACSINE Institute and Protiostasis Therapeutics.
- Since last two months I am working on project sponsored by International AIDS & VACSINE Institute US. One of the leading pharmaceutical company developing new class of medicines based on RNA technology, where I have gained experience of working on reactions from a few mgms to 500 gm scale
EDUCATION :
M.Sc. (Organic Chemistry)
June 2008 First Class with Distinction (70.25%).
Ahmednagar College Ahmednagar
B.Sc. (Chemistry, Physics, Botany,)
June 2006 First Class with Distinction (86.16%).
University of Pune.
H.S.C. June 2002 First Class (65.00 %)
University of Pune.
S.S.C June 2000 First Class (68.00 %)
Shriram high school Bhanashiware
Nature of Work
- Carrying out Multi step synthesis of various organic molecules
- Synthetic experience from milligram to gram scale.
- Isolation of different Organic compounds by using different techniques such as Column Chromatography, flash column chromatography, Crystallization, and High vacuum Distillation.
- Ability in characterization of Organic Compound through various spectroscopic
Techniques such as 1H NMR, 13C NMR, Mass, LC-MS, IR, HPLC etc.
- Distillation of dry solvents such as THF, DCM, DMF, Pyridine, MeOH etc
- Knowledge in literature tool like Beilstein, Scifinder and reaxys along with Chemdraw, ISIS draw and Parrallel synthesizer.
Experimental knowledge
- Hydrolysis, Bromination, Hydrogenation, Reductive amination etc.
- Moisture-sensitive reactions involving reagents such as Butyl-lithium, Sodium hydride, Sodium Borohydride, Palladium on charcoal, Lithium Aluminum hydride. PCC oxidation.
- Protection reaction involving protecting group like TBDMS, TMS-Cl, CBzCl, & Boc anhydride.
- Carried out various named reactions like Suzuki coupling, DCC coupling, and Grignard reaction to name few.
- Ability to work in group as well as independent.
PRESENTATION AND SKILLS SETS :
- Delivered seminar on “Gastrointestinal tract disorders” Which includes, Peptic ulcer, Nausea & Vomiting, Diarrhea, and Constipation in the Ahmednagar College Ahmednagar. University of Pune. March 2008.
Research Interest :-
- Synthetic Organic Chemistry, Carbohydrate Chemistry, Synthesis of Biologically Active Compounds, Synthesis of Natural Products, Bioorganic Chemistry, combinatorial chemistry

[Guest]

CURRICULUM VITAE
Pradip kadam.
Email id :
Pradip.kadam27 AT gmail.com
Pradip_kad AT rediffmail.com
Career Objective :

I am seeking a challenging position with a company that is rapidly expanding and offer good advancement potential. I would like a position that would help me progress and bring the best in me.
RESEARCH SKILLS :
- Excellent skills in handling air-sensitive reagents/reactions, isolation and structural, elucidation of organic compound by spectroscopic methods.
- Expertise in analyzing 1D NMR (1H NMR, 13C NMR), 2D NMR (COSY, NOESY, DEPT, HSQC, Mass, IR and UV spectral data for structural determination of un-expected products.
- Conversant with commonly used computer software’s : MS-Office and Chemdraw.
Education :
- Master of Organic Chemistry (65.5%) from Sangamner College, Sangamner. Pune University, Maharashtra
- Bachelor of Science (69.33%) from Shivaji University Kolhapur, Maharashtra.
- Higher Secondary Exam (10+2), 59.00% From Phaltan shivaji vniversity kolhapur.

Work Experience :
1) Worked as Research Associate (R&D department) in reaserch support international limited (Evotec India Ltd Thane.) As Research chemist From Aug 2008 to Feb 2010, (1.6 Years)
Job profile :
- Performing micro reaction on milligram & gram scale of complex molecule. (Synthesis)
- Updating project reports.
- Individually handle the complex project of good chemistry.
2) Worked as Glen-mark Pharmaceutical Ltd. From March 2010 to March 2011 as Research chemist. (1 Year)
3) Currently working as Project Assistant in ICT, Mumbai. From March 2011 to till date.

Name Reaction :
Friedal Craft Alkylation and Accylation, Mitsunobu reaction, Nitration reaction, Halogenation, Amide formation, Diazotisation reaction,Reductive amination, Reduction and Oxidation reaction,N-methylation reaction, Cyanation reaction, handled various reagents like, n-BuLi, NaH, LAH, NaBH4, DIBAL-H and Na metal.
Coupling Reaction such as :
Suzuki coupling, stille coupling, Buchwald Coupling, Acid-Amine coupling (HOBT, EDCI), Heck reaction.
Protection and Deprotection reaction with : Acid, Amine, Alcohol, carbonyl group.
Instrument handled
- Combiflash chromatographer.observation
- Microwave (Biotage And CEM Discovery).
Computer knowledge
- Knowledge of basics of Computer & Internet. (Window 2000/XP)
Area of interest
R & D (Organic Synthesis)

[Unregistered]

respected sir, could a DMLT passed, B.Sc MLT Student can apply for job in your organisation?