Naari AG Noida : R&D Research Associate

[Rajkumargautam]

NAARI AG Noida : R&D - Research Associate

Designation: R&D - Research Associate
Experience: 1 - 3 Years
Location: Noida

Job Description:
• Performing chemical experiments
• Preparation of Technology Transfer Documents.
• Literature survey as and when needed.
• Lab Management as per the GLP norms
• To maintain proper documents of the work carried out and other observations of various experiment in Lab.

Desired Candidate Profile:
• Good knowledge of synthetic organic chemistry.
• Should be able to work in a team.
• Experience in API development will be an advantage.

Company Profile:
Our company, Naari AG is a Swiss pharmaceutical company and poised with a vision to become a major integrated female health care organization specializing in hormones and steroids, NAARI brings to you a range of hormonal and steroid products that cater to all the needs of a woman.

Naari is building up a strong marketing and distribution network across the globe and is entering in agreements with reputed distributors making company reach global .Our product portfolio include solid orals contraceptives, emergency contraceptives, abortion pills Hormones for HRT therapy ,drugs for endometriosis, injectable hormonal contraceptive birth control drugs along with hormonal APIs and intermediates .

Our USP is that we are the only Company in the country which manufactures some of the hormonal APIs from scratch including intermediates, starting from the Raw Materials and therefore we are in a position to supply international quality products at extremely competitive and affordable prices.

Address:
C-82 Hoisery Complex Phase II Noida UP 201305
Noida,UP,INDIA 201305

Email Address: ruchika.sharma@naari.ch
Website: http://www.naari.ch

Keywords: R&D Chemist, R&D Associate, Research Associate

[Guest]

ASTHA SINGH BAGHEL
CONTACT NO.– 09907674429
EMAIL ID - aasthasingh33@yahoo.com

Objective

To grow within a company fueled with new and innovative ideas & to became an asset for organization by delivering value to the organization through my knowledge base.

Academic Qualification

1. High School – Passed in first div. With 70% from MP board.
2. Higher Secondary – Passed in first div. With 73% from MP board.
3. Under graduation – B.Sc.(hons.) in Chemistry & Subsidiary Physics with 75% aggregate from excellence college affiliated to A.P.S. University.
4. Post graduation – M.Sc. in chemistry with elective papers Medicinal and Analytical, appearing in final year exam from I.P.S. Academy affiliated to D.A.V.V. Indore.

Skills

Computer skill –
Basic knowledge of computer
Language - BASIC , C ,C++ , VISUAL BASIC
Language known – Hindi, English

Apparatus Handling
colorimeter, PH-meter, Polarimeter, HPLC, Spectrophotometer, FTIR etc.

Extra Curricular Activities

1. Participating in chemical science workshop on “Future Prospects & Recent Techniques in Chemical Science”.
2. Participate in science fair and stood 2nd position in that.
3. State level games participation.
4. Participation in National School Games.

Personal Details
Fathers name – Mr.G.S.Baghel
Occupation –Govt. service
Date of birth – 03-05-86
Martial status –Single
Permanent Add. – 2-Jagdeo Vihar , beside gun factory,NH-7,dhekha,rewa(m.p.)

References
1. Mr. Bhanu Pratap Singh , national account manager. H.P. India sales private ltd., New Delhi.
2. Miss Swati Singh,Solution Architect,Tribal Fusion.com,Noida


ASTHA SINGH

[Guest]

Curriculum vitae
RICHU SINGLA

Working E-mail : richu.singla AT thapar.edu , Personal Email: richussingla AT gmail.com
Multiple entry business visa B1 for US valid upto 29 September 2020

Objective :

I am working in the field of Biotechnology. I have negotiating and organizing skills, a firm sense of responsibility and my capacity to work hard under pressure during my project work.

Research Experience :
1) Thapar University Patiala, PUNJAB 11th Jan 2007- Till Date
Working as a Research Scholar at Thapar University Patiala, Punjab on “Study of high risk bacterial pathogens in Indian fresh produce and development of novel inactivation strategies.”
Abstract :
- Characterization of selected microbial pathogens in Indian fresh produce and identify the possible entry points in their farm–to-plate chain.
- Determine the suitability of organic acids, ozone treatments or combined sanitizer treatments for inactivation of key pathogens in selected fresh produce through well-designed simulation studies.
- Understand and elucidate the behavior of acid resistant pathogens in fresh produce and consequently establish appropriate treatment regime for intervention.
- Determination of the final combined effect of treatment process on pathogens, resident microbes and on essential quality characteristics of produce.
2) S.B.S.P.G.I. Dehradun, Uttarakhand 1st Jan 2006-31st June 2006
Characterization of Heat Shock Proteins, Proline content and Callus induction in Groundnut (Arachis hypogaea L.) Seedlings
Abstract :
- Determine germination profile of cytoplasmic proteins in groundnut seedlings.
- Optimize protocol for callus induction from different organs of groundnut seedlings.
- Determine effect of temperature on the cytoplasmic proteins in different organs of groundnut seedlings taken from transitional stage.
- Analyze SDS-PAGE profile of cytoplasmic proteins in leaves of heat shock treated leaves of groundnut seedlings.
- Asses amino acid composition of heat shock related cytoplasmic polypeptides through paper chromatography.
- Confirm the level of stress amino acid proline in leaves and heat shock related polypeptides.
Project undertaken :
- Worked for two years (2008-2010) in MFPI (Ministry of Food Processing Industries, Govt. of India) aided project “Development of a Minimal Processing Technology for High Quality Edible Mushrooms”
- Professional bodies membership :
AFSTi membership for the year 2011
Awards/ Honours :
- Awarded full travel grant to attend “International Food Symposium” at University of Wisconsin, River Falls USA by “Council of Scientific & Industrial Research, Human Resource Development Group (HRDG)
- Awarded “Council of Scientific & Industrial Research-Senior Research Fellowship 2010” (CSIR-SRF) by Human Resource Development Group (HRDG)
- Selected for “Rajat Jayanti Vigyan Sancharak Fellowship 2009” by Department of Science and Technology, Ministry of Science and Technology
- Final Selection for the “RISE program 2009” by Indo-US Science and Technology Forum
- Scored 1st or 2nd position during all the four semesters of Post-Graduation.
- Scored 1st position during graduation 1st year.

Teaching Experience :
Worked as Teaching Assistant at Thapar University which includes organizing practical classes with B. Tech./M.Sc./ M.Tech students based on Molecular Biology, Immunology, Food microbiology, Biochemistry, Biotechniques, Cell Biology, Pharmachemistry, and Fermentation from 01-02-2008 to 30-06-2008, 01-08-2008 to 31-12-2008 and 27-07-2009 to 31-10-2009.
Publications : Published/Accepted:
Richu Singla, Abhijit Ganguli and Moushumi Ghosh (2011). Inhibition of biofilm formation by Salmonella typhimurium on food contact surfaces using malic acid and ozone. Journal of Food Protection (accepted)
Richu Singla, Abhijit Ganguli and Moushumi Ghosh (2010). Combined organic acid and ozone inactivates Shigella spp. in sprouts but retains antioxidant activity. Food Control, Volume 22 Issue 7, 1032-1039 doi :10.1016/j.foodcont.2010.12.012
Richu Singla, Abhijit Ganguli and Moushumi Ghosh (2010). Antioxidant activities and polyphenolic properties of raw and osmotically dehydrated dried mushroom (Agaricus bisporous) snack food. International Journal of Food properties, Volume 13, Issue 6, 1290-1299
http http://://pdfserve.informaworld.com/..._927392724.pdf
Richu Singla, Abhijit Ganguli and Moushumi Ghosh (2010). Physicochemical and nutritional characteristics of organic acid treated button mushrooms (Agaricus bisporous). Food and Bioprocess Technology, DOI : 10.1007/s11947-010-0457-7
Richu Singla, Abhijit Ganguli, Moushumi Ghosh and Sapna Sohal (2009). Evaluation of sanitizing efficacy of acetic acid on piper betle leaves and its effect on antioxidant properties. International Journal of Food Sciences and Nutrition, Volume 60, No. s7, 297-307.
URL : http://dx.doi.org/10.1080/09637480903114110
Richu Singla, Moushumi Ghosh and Abhijit Ganguli (2009). Phenolics and Antioxidant Activity of a ready-to-eat snack food prepared from the edible mushroom, Agaricus bisporous. Nutrition and Food Science, Volume 39, No. 3, 227-234. URL : http://www.emeraldinsight.com/10.1108/00346650910957474
Richu Singla, Jitendra Singh Baliyan, D. Kumar (2007). Heat shock proteins (HSPs) and acquisition of thermotolerance in higher plants. Int. J. Plant Sci. 2 (2) 252-257.

Conference / Workshop Attended :
Singla R, Ganguli A, and Ghosh M. Microbial safety, shelf life and nutritional quality of organic acid treated Button Mushrooms (Agaricus Bisporous). International Conference on Food Research (ICFR 2010), 22-24 Nov. 2010. Universiti Putra Malaysia, Putrajaya, MALAYSIA
Singla R, Ghosh M and Ganguli A. Survival, growth and transmission of Cronobacter (Enterobacter) sakazakii in rice and cereal based weaning foods. International conference on frontiers in biological sciences (InCoFIBS-2010). 01-03 Oct. 2010. NIT Roukela, Orisa (Oral Presentation)
Participated in International conference on post harvest management and valorization Agri-Horticultural produce and exhibition. 19-20 Feb. 2010. NASC Auditorium Dev Praksh Shashtri Marg, New Delhi
Singla R, Ganguli A. Evaluation of acetic acid as sanitizer for reducing Shigella flexneri in sprouts and its effect on antioxidant properties. 50th Annual AMI conference. 15-18 Dec. 2009. NCL Pune (Poster presentation
Singla R, Mittal P, Ghosh M and Ganguli A. Prevalence of Aeromonas and Yersinia spp. in some commonly consumed selected Indian fresh produce. National symposium on Emerging trends in Biomedical Sciences. 27-28 Feb. 2009. SBSPGI Dehradun (Oral presentation)
Singla R, Ganguli A and Ghosh M. Antioxidant activities and polyphenolic properties of raw and vacuum dried button mushroom (Agaricus bisporous) snack food. 16th International drying symposium 2008. 9-12 Nov. 2008. Sitara Hotel, Ramoji Film City Hyderabad (Oral presentation)
Singla R, Baliyan J.S. Heat responsive polypeptides in groundnut (Arachis hypogaea L.) seedlings. National conference on Microbial Diversity Avenues and Applications. 17-18 March 2007. SBSPGI Dehradun (Oral presentation)
Short course on “Yeast molecular biology and biochemical analysis” organized by department of biotechnology and bioinformatics, Jaypee university of information & technology, Waknaghat, HP in association with Institute of molecular sciences, Frankfurt University, Germany. July 23-27, 2009
CME/Workshop in “VIROCON 2008” (XVIII National Conference of Indian Virological Society) organized by department of Virology, Post Graduate Institute of Medical Education & Research, Chandigarh, India, Dec. 11, 2008.
Singla R, Singh J. Characterization of heat shock proteins (HSPs) and callus induction in groundnut (Arachies hypogoea L.) seedlings. APSI Scientist’s Meet and National Conference-2006 on New Vistas in Microbiology and Plant Sciences. September 19-20, 2006.
Technical Expertise :
Microbiology –
- Bright field microscopy
- Bacterial staining, aseptic technique
- Cytological techniques
- Media and buffer preparation - Streak plating, media preparation and gram staining, enzyme assay
- Basic biochemical tests
- Isolation and characterization of Microbes
Molecular Biology –
- DNA extraction and purification
- Polymerase Chain Reaction
- Recombinant DNA manipulation
- Dialysis - Electrophoresis
- Restriction digestion
- Transformation
- Chromatography techniques
Other -
- Rational knowledge of ELISA
- Immunodiffusion - Plant Tissue culture
- Working knowledge of Windows,
MS-Office, Internet browsing
References :
1. Dr. Abhijit Ganguli (Assistant Prof.) Department of Biotechnology and Environmental Sciences, Thapar University, Patiala, Punjab. India Email :ganguliabhijit AT rediffmail.com, Phone No. 91-175-2393449
2. M. Vasundhara Reddy (Assistant Prof.) Department of Biotechnology and Environmental Sciences, Thapar University, Patiala, Punjab. India Email :mvasundhara AT thapar.edu Phone No. 91-175-2393269
3. Dr. Anita Rajor (Assistant Prof.) Department of Biotechnology and Environmental Sciences, Thapar University, Patiala, Punjab. India Email :anitarajor AT yahoo.com, Phone No. 91-98-72453360
Educational Qualifications :
College/University Course/Level/Subjects studied % age Division
HNB Gharwal University, Gharwal 2004-2006 M.Sc. Biotechnology
78.95
1st
Punjabi University,
Patiala 2001-2004 B.Sc.
Botany, Chemistry, Zoology, English, Punjabi
68.96
1st
Punjab School Education Board, Mohali
2000 Intermediate
Physics, Chemistry, Botany, Zoology, English, Punjabi
67.11
1st

Punjab School Education Board, Mohali, 1998 High School
English, Hindi, Social Science, Science, Mathematics, Punjabi
77.84
1st

[Guest]

CURRICULUM VITAE

Rajesh Kumar Singh
E-MAIL :
rajmedichem AT gmail.com
rajmedichem AT gmail.com


CAREER OBJECTIVE :-
1- To accomplish challenging task in an organization by making best use of my knowledge there by catalyzing the growth of organization & self. I am very much looking forward to any challenging opportunity with a dramatic organization and seeking to obtain a position in on innovative leadership which can provide me an opportunity to rise in confidence and explore wide arrange of knowledge and working skills and experience.
2- Good problem solving skills and the ability to work effectively as part of a scientific team.
3- Demonstrated abilities to take initiative think and work independently, in a diverse, demanding, and exciting technology environment.
RESEARCH PROFILE :-
- Field of Research - "Synthetic Organic Chemistry and Medicinal Chemistry"
- Presently Working as Research Associate in Jubilant Chemsys Ltd. (CRO) Noida.
CURRENT POSITION :-
Jubilant Drug Discovery & development Ltd, Noida :
Jubilant is India’s largest and fastest growing pharmaceutical company offering medicinal chemistry services in drug discovery portfolio and development programs within a short span of time, achieved a rare distinction of becoming the fastest growing Chemistry service provider in India. The company synthesizes a number of molecules in a day, which have a strong therapeutics screens like Antibiotics, Antifungal, Anticancer, Antimalarials, Cardiovascular, CNS screens.
Designation : Research Associate
Role : Research and Development in Organic Synthesis,
ROLE & RESPONSIBILITIES :-
- Ability to manage all the assign projects independently, including chemistry exploration, route optimization and troubleshooting along with a team of 3-4 Research Associates.
- Responsible in process development by synthesizing small to large scale quantities of compounds to support the needs of discovery scientists and initial pre-clinical studies and working with process chemistry in solving challenges associated with the chemistry.
- Focus on improving the optimum process and technology to synthesizing the promising compounds and on making the compounds efficiently, cost-effectively, and in the safest manner.
- Major focus on cheap, environmentally benign and readily available starting materials, reagents and catalysts.
- At present handling the various library/Med. Chemistry projects.
- Interaction with the clients periodically for project requirements, clarifications, progress and updates.
- Synthesis of molecules as per the defined route or define the route to synthesize the molecules.
- Documentation, and literature searches supporting research, is also key components of my role .Documentation part deals with the making weekly and final report of the particular project and also.
.
- Familiar in using modern synthetic organic methodology, chromatographic techniques, and spectroscopic techniques and high vacuum Distillation to purify and characterize the desired product.
- Proficient with recrystallization technique to isolate high pure product.
- To maximize the Yield outputs (Cost reductions) and reducing the time cycle of process by effective method.
- Synthesis of novel scaffolds of any structural complexity and flexible approach to produce novel building blocks and reference compounds.
- Lab Management as per the GLP norms.
- Coordinating with IPR department for Lab note book maintenance.
- Responsible for maintaining the confidentiality of the project as per the IPR guidelines.
- Maintaining and improving Health and Environmental standards.
PROJECT WORK :-
I have done other reactions like protection and deprotection and amide bond formation means acid- amine coupling reaction with various coupling reagents such as EDC, T3P, HATU, HBTU etc, including acid chloride route. I have also involved in the synthesis and cost reduction of some API drugs and very much familiar with oxidation and reduction reaction. Successful handled big libraries (more than 40 molecules).
RESEARCH EXPERTISE :-
- Very much familiar in general type reactions like as …
Electrophilic substitution, Nucleophilic substitution, Friedal-crafts alkylation and
acylation, alkylation, halogination, esterification, epoxidation, oxidation, reductions,
decarboxylation, cyanation using sodium cyanide and potassium cyanide, wittig
Reaction,coupling reactions and Catalytic reductions (Pd) etc.
- Expertise in handling other various reactions/regents :
- C-C/C-N Coupling : Suzuki, Buchwald, Negishi, Stille, Sonogashira, Grignard, etc.
- Oxidation : Swern oxidation, MnO2, KMnO4, Dess-Martin, MCPBA
- Reduction : Hydrogenation [Pd-C,Pd(OH)2,Raney-Ni,LiAlH4, NaBH4, NaCNBH4, NaBH(OAc)3,

- Halogenation : Bromine, NBS, POCl3, POBr3, PBr3, PCl5.
- Organo-lithium reagents : n-BuLi, LDA t-BuLi.
- Protection-deprotection :Boc,CBZ,Benzyl,
- Other reaction : Peptide Coupling (EDC.HCl, HATU, T3P, HOBt, etc.
Efficiency in performing moisturesensitive reactions(i.e.Grignard reaction, BuLi etc) and good practical command in Wittig reaction.

ACADEMIC QUALIFICATION :-

- 10th passed from U.P Board with 1st division in 2001.
- 12th Passed from U.P Board with 1st division in 2003.
- B-Pharma (1stdivision) from Rajeev Gandhi University of Health Science. Bangalore.
- M-Pharma (1stdivision) from Jaipur National University, Jaipur.
WORK EXPERIENCE :-
SEVEN MONTH work experience in Hazen pharmaceutical ltd,Hydrabad in Q.A DEPARTMENT as a post of Q.A officer.
INDUSTRIAL VISITS :-
- K.P. pharmaceutical ltd, Bidar, Karnataka
- Hazen pharmaceutical ltd ,Hydrabaad
- SATWIK (BULK DRUGS) Bidar, Karnataka
AREA OF RESEARCH :-
Chemical Standardization and Biological activity of Coscinium fenestratum from National Botanical Research Institute, Lucknow (U.P)
OTHER ACHIEVEMENTS :-
Campus selected for Jubilant chemsys ltd,Noida.
COMPUTER PROFICIENCY :-
Basic Knowledge of Computer with Desktop Management Skills means easy asses of Computer Windows XP, MS-OFFICE, Excel, Power Point (For making the weekly update, report and lecture presentation).Various chemistry software and Internet applications.
WORK KNOWLEDGE :-
1-IN FIELD OF HERBAL:-
- Standardization and identification of HERBAL DRUG with how much amount of major active constituent present in particular part of plant with determination of foreign materials.
- Purification of crude herbal drug or crude compound by using Flash chromatography (Biotage/isolera).
- Quantification of major active constituent present in crude drug by using H.P.T.L.C (CAMMAG).
2- IN FIELD OF SYNTHESIS:-
- Experience in organic synthesis: novel approaches to various heterocyclic and biologically active compounds.
- Purification technique of synthesized organic compounds by using High vacuum Distillation, Column chromatography (silica, alumina, and reverse phase), flash chromatography, Prep TLC, Prep HPLC, and MS directed Prep HPLC, Recrystalization etc.
- Expertise in several techniques for the synthesis and purification of various classes of organicmolecules.
- Experience in handling of various library / medicinal chemistry projects.
- Structure elucidation by analyzing data from proton or carbon NMR, LCMS and MASS.
- To synthesize the target molecules as per the designed synthetic route.
- Experienced in the synthesis of biologically active compounds at milligram scale to kilogram scale.
- Familiar with techniques of Combiflash, Biotage purification system.
- Very well handling the microwave for its use in the organic synthesis.

[Guest]

Divya Ksansal

OBJECTIVE
Seeking to handle increasing responsibility and challenging assignment to harness my technical skills, knowledge with minimal supervision to meet timelines.
INDUSTRIAL EXPERIENCE
June 2006- November 2010
Worked as a Research Associate in Quality Assurance & Regulatory Deptt. at R&D Centre, Ind-Swift Labs Ltd, Mohali, Punjab.
TRAININGS
- Attended one week training program on Good Laboratory Practices (GLP) at NIPER.
- Attended two days program on Internal Auditor training course.
JOB RESPONSIBILITIES
- Preparation of Technical packages for APIs.
- Preparation of Customer data base including customer enquiries, customer questionnaires, samples/working standard and impurity standard.
- Preparation of Open Part of Drug Master File.
- Compilation of Drug master file.
- Submitted DMFs in eCTD format.
- Preparation of DCGI applications.
- Submission of sample to Indian institute of Toxicology for toxicological studies.
- Compilation and maintenance of data base for vendor documents.
- Preparation of response for regulatory queries.
- Review of BPRs and change control.
- Review of CRD documents like Technology transfer documents.
- Review of Analytical Method Validation reports and Stress Study Reports.
- Review of ARD documents like standard operating procedure, specification and method of analysis of raw material, in-process, intermediate and final API.
- Review of stability protocol, report and supervise maintenance of stability documents/samples and timely issuance of samples to ARD division for the analysis.
- Review of the stability results and timely submit to the concerned departments.
- Supervise issuance and maintenance of documents and formats to DRA, ARD, CRD and Plant-QA, retrieval of superseded documents.
- Supervise timely issuance of the samples of API’s, Intermediates, and working standards of API, Impurities to customers and Plant-QA.
- Supervise issuance of lab note books, document numbers to ARD and CRD and assigning of product code to all new APIs.
- Supervise Maintenance of Training records/Amendments records and their closure.
- Worked in Customer Support Cell for one month.
- Basic Knowledge of ICH guidlines
ACADEMIC CREDENTIALS
Particulars Institute/ University Year Class/Grade
MBA in Total Quality Management National Institute of Management
(ISO 9001 : 2008 Certified International B –School) 2010 A Grade
MSc. Industrial Chemistry G.N.K College, YamunaNagar 2006 First (62.7%)
BSc. Medical M.L.N College, YamunaNagar
2004 First (63.4%)
Senior Secondary School Examination M.V.M Public School , YamunaNagar 2001 First (70.4%)
Secondary School Examination M.V.M Public School , YamunaNagar 1999 First (77.8%)
COMPUTATIONAL SKILLS
- MS office i.e. MS Word, Microsoft Excel, Power Point presentation
- Practical knowledge of software like Chem. Office
- Well versed knowledge with Internet
- Operating Systems : Windows

[Guest]

details and applying procedure of vacancy