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[QUOTE=hemalathaijt;201723][B]Name of the organisation[/B] : Pacific university (pacific-university.ac.in)
[B]Description [/B]: Model Question Paper
[B]
Index Page[/B] : [URL]http://pacific-university.ac.in/Content.aspx?Page=Research_and_P.hd[/URL]
[B]Model Question Paper[/B] : [URL]http://pacific-university.ac.in/Userfiles/Documents/Biotechnology.pdf[/URL]

[B]Sample Paper
PhD Section B Biotechnology
Max. Marks 100[/B]
Attempt all 50 questions, each question carries 02 marks. There is no negative marking. Please mark the correct answer as A/B/C/D at appropriate place, on the right hand side of the question, in blue or black.
1. Bacterial genomes is prevented by its own endonucleases by-
(A) Methylation at restriction sites
(B) Immune mechanism
(C) Nuclease resistant genome
(D) Are not much effective on bacterial genome

2. The difference which distinguish prokaryotic cell from eukaryotic is-
(A) ER
(B) Mesosome
(C) Nuclear Membrane
(D) Plasma membrane

3. Holiday junction is observed during:
(A) Mitosis
(B) Interphase
(C) Recombination
(D) DNA Repair

4. Presence of AIDS virus cannot be detected by-
(A) ELISA
(B) Western blotting
(C) Northern Blot
(D) Assay of full-length ds DNA

5. Which part of translational modification of proteins does not occur in lumen of ER
(A) Glycosylation
(B) Ubiquitnation
(C) Conformation folding & formation of quaternary structure
(D) Formation of Disulphide bonds

6. Which one of the following is correct for structure of cell wall of fungi and Bacteria?
(A) Both have glycopeptides
(B) Both are made up of N-acetylglucasamine
(C) Both are made up of murin
(D) Both are made up of chitin

7. Among the following which is true cell according cell theory2
(A) Virus
(B) Monerans
(C) Protestans
(D) Bacteria

8. The outer part of cytoplasm is usually termed as-
(A) Plasmasol
(B) Plasmagel
(C) Nucleoplasm
(D) Protoplasm

9. Polyribosome are seen in-
(A) Bacteria
(B) Fungi
(C) Angiosperms
(D) Mammals

10. Which of the following is correct with regard to aneuploidy?
(A) Inversion
(B) 2n + 1
(C) All aneuploid individuals die before birth.
(D) 4n

11. Which of the following is an example of a hydrophobic material?
(A) Paper
(B) Sugar
(C) Pasta
(D) Wax

12. Among the following which is longest cell-
(A) Hemp
(B) Ramie
(C) Jute
(D) Nerve fibre

13. The percentage amount of Integral protein of plasma membrane is-
(A) 40 %
(B) 50 %
(C) 60 %
(D) 70 %

14. Post translation modification of secretary proteins occurs in:
(A) RER
(B) SER
(C) Mitocondria
(D) Nucleus

15. How you can separate Gram + ve bacteria from Gram –ve bacteria-
(A) Presence of Techoic Acid
(B) Absence of periplasmic Space
(C) Exotoxin Produced
(D) All of the above

16. Number of antigen functional binding site in human Immunoglobin-M are-
(A) 2
(B) 5
(C) 10
(D) 20

17. Lymphokines that recruit the macrophages for Phagocytosis are secreted by-
(A) T-cells
(B) B-cells
(C) Complement system
(D) MHC

18. Which among the following act as bridge between cell mediated and humoral immunity-
(A) T-cytoxic cells
(B) T-suppressor cells
(C) B-cells
(D) T-helper cells

19. A researcher made an interesting observation about a protein made by the rough ER and eventually used to build a cell’s plasma membrane. The protein in the membrane was actually slightly different from the protein made in the ER. The protein was probably  changed in the
(A) Golgi apparatus.
(B) Smooth ER.
(C) Mitochondrion.
(D) Nucleus.

20. Mark the incorrect statement: Ribozyme and Abzyme are
(A) Both enzymes
(B) Both proteins
(C) RNA and protein respectively
(D) Able to hydrolyse phosphodiester and peptide bonds respectively[/QUOTE]

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