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[QUOTE=hemalathaijt;192484][B]Document Described : Alagappa University
DISTANCE EDUCATION
M.Phil.  (Zoology) DEGREE EXAMINATION, MAY 2011.
(Non-Semester)
RESEARCH METHODOLOGY AND LABORATORY TECHNIQUES
(2006 Batch)[/B]
[B]Time [/B]: Three hours[B] Maximum[/B] : 100 marks

[URL]http://www.alagappauniversity.ac.in/examination/model_question_paper_details.php?paper_month_id=9&college_id=2[/URL]
[URL="http://www.alagappauniversity.ac.in/files/question_paper/2-M.Phil%20%28Zoology%29.doc"]http://www.alagappauniversity.ac.in/files/question_paper/2-M.Phil%20(Zoology).doc[/URL]

Answer any FIVE questions.
All questions carry equal marks.
(5 ? 20 = 100)

1.Give an account on principal and applications of light microscopy and electron microscopy.

2.Discuss about the principle and operation method of pH meter and add a note on preparation of buffers.

3.Critically evaluate the followings :
(a)Effect of Radioactive isotopes on biological system
(b)Principles of liquid scintillation counter.
(c)Application of various radioactive isotopes in  biological systems.
(d)Application of autoradiography.

4.Discuss the principle, method and application of HPLC.

5.Give an account on immune diffusion and Hybridoma technology.

6.Write notes on different types of blotting techniques and their applications.

7.Comment on the following :
(a)Gene and Genome
(b)Protein and Proteomes
(c)Drug designing
(d)Genomics to proteomics.

8.Describe the principle and application of X-ray diffraction.[/QUOTE]

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